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Association of SNPs in miR-146a, miR-196a2, and miR-499 with the risk of endometrial/ovarian cancer

MicroRNAs (miRNAs) are a class of small non-coding RNA molecules (containing N22 nucleotides), which function in RNA silencing and post-transcriptional regulation of gene expression [1]. miRNAs have been reported to play a key role in tumorigenesis [1], Some single nucleotide polymorphisms (SNPs) in...

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Bibliographic Details
Published in:Acta biochimica et biophysica Sinica 2015-07, Vol.47 (7), p.564-566
Main Authors: Liu, Xiaoyan, Xu, Beihui, Li, Shujin, Zhang, Bin, Mao, Peimin, Qian, Beibei, Guo, Lin, Ni, Peihua
Format: Article
Language:English
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Summary:MicroRNAs (miRNAs) are a class of small non-coding RNA molecules (containing N22 nucleotides), which function in RNA silencing and post-transcriptional regulation of gene expression [1]. miRNAs have been reported to play a key role in tumorigenesis [1], Some single nucleotide polymorphisms (SNPs) in miRNA genes can influence the generation or function of miRNAs, and thereby possibly affect tumor growth and development.
ISSN:1672-9145
1745-7270
DOI:10.1093/abbs/gmv042