Central versus peripheral arterial cannulation and neurological outcomes after thoracic aortic surgery: meta-analysis and meta-regression of 4459 patients

Background: Thoracic aortic surgeries remain with high mortality rates, often associated with postoperative neurological complications. The choice of the right cannulation site is extremely important for suitable blood supply and maintenance of vital functions, especially of the central nervous syst...

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Bibliographic Details
Published in:Perfusion 2015-07, Vol.30 (5), p.383-388
Main Authors: Chalegre, ST, Sá, MPBO, de Rueda, F Gonçalves, Salerno, PR, Vasconcelos, FP, Lima, RC
Format: Article
Language:English
Subjects:
Age Factors
Aorta, Thoracic - surgery
Cardiac Surgical Procedures - adverse effects
Cardiac Surgical Procedures - methods
Catheterization - adverse effects
Catheterization - methods
Data Mining
Female
Humans
Male
Nervous System Diseases - etiology
Nervous System Diseases - mortality
Postoperative Complications - etiology
Postoperative Complications - mortality
Sex Factors
Software
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Summary:Background: Thoracic aortic surgeries remain with high mortality rates, often associated with postoperative neurological complications. The choice of the right cannulation site is extremely important for suitable blood supply and maintenance of vital functions, especially of the central nervous system. Objectives: To compare the influence of central versus peripheral arterial cannulation on neurological outcomes in patients undergoing thoracic aortic surgery through systematic review and meta-analysis. Methods: MEDLINE, EMBASE, CENTRAL/CCTR, SciELO, LILACS and reference lists of relevant articles were searched for clinical studies that reported in-hospital neurological outcomes after central or peripheral arterial cannulation during thoracic aortic surgery procedures until December 2013. The principal summary measures were Odds Ratio (OR) for central compared to peripheral arterial cannulation with 95% confidence interval (CI) and p-values considered statistically significant when 0,05. Conclusion: When it comes to neurological outcomes in patients undergoing thoracic aortic surgery, there was no evidence that argues in favor of any choice of arterial cannulation site, which makes us reject any superiority of one approach over the other in this regard.
ISSN:0267-6591
1477-111X
DOI:10.1177/0267659114547379