No increased bleeding risk for oral surgery in patients with severe congenital bleeding disorders due to intense perioperative management

Purpose In order to evaluate complication rates of dentoalveolar surgery in patients with congenital bleeding disorders, a retrospective case–control study was performed. Methods A collective of patients with congenital bleeding disorders ( n  = 69), who received common oral surgery procedures in co...

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Bibliographic Details
Published in:Oral and maxillofacial surgery 2015-06, Vol.19 (2), p.195-200
Main Authors: Goldmann, G., Berens, C., Marquardt, N., Reich, R., Oldenburg, J., Wenghoefer, M.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Blood Coagulation Disorders, Inherited - complications
Blood Coagulation Disorders, Inherited - drug therapy
Blood Coagulation Factors - administration & dosage
Blood Loss, Surgical
Child
Child, Preschool
Dentistry
Female
Germany
Hemostasis, Surgical - methods
Humans
Male
Medicine
Medicine & Public Health
Middle Aged
Operative Time
Oral and Maxillofacial Surgery
Oral Surgical Procedures
Original Article
Perioperative Care - methods
Postoperative Hemorrhage - prevention & control
Young Adult
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Summary:Purpose In order to evaluate complication rates of dentoalveolar surgery in patients with congenital bleeding disorders, a retrospective case–control study was performed. Methods A collective of patients with congenital bleeding disorders ( n  = 69), who received common oral surgery procedures in combination with intense perioperative monitoring and coagulation factor substitution at the University Hospital of Bonn between 1992 and 2011, was matched with patients without bleeding disorders by age, sex, and type of surgery. In addition to the rates of perioperative bleeding and other complications, the duration of surgery and the use of local hemostatic agents were compared between both cohorts. Results There were no significant differences between the two groups regarding the rate of postoperative bleeding (2.9 vs 1.4 %, patients with congenital bleeding disorders vs controls) and the rate of other complications (7.2 vs 21.7 %). Furthermore, no significant difference in operation time (54 min in patients with congenital bleeding disorders vs 45 min in controls) was observed. However, there was a significant difference ( p  
ISSN:1865-1550
1865-1569
DOI:10.1007/s10006-014-0476-z