Incidence and risk of mood disorders in patients with breast cancers in Taiwan: a nationwide population-based study

Objective The objective of this study is to assess the incidence and risk of mood disorders, including major depression, anxiety, and bipolar disorders, in Taiwanese patients after the diagnosis of breast cancer compared with a matched cohort. Methods From January 2000 to December 2005, 26,629 newly...

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Bibliographic Details
Published in:Psycho-oncology (Chichester, England) England), 2013-10, Vol.22 (10), p.2227-2234
Main Authors: Hung, Yi-Ping, Liu, Chia-Jen, Tsai, Chia-Fen, Hung, Man-Hsin, Tzeng, Cheng-Hwai, Liu, Chun-Yu, Chen, Tzeng-Ji
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aged, 80 and over
anxiety
Anxiety Disorders - epidemiology
Anxiety Disorders - psychology
Autoimmune Diseases - epidemiology
Bipolar Disorder - epidemiology
Bipolar Disorder - psychology
bipolar disorders
Breast cancer
Breast Neoplasms - epidemiology
Breast Neoplasms - psychology
Case-Control Studies
Cerebrovascular Disorders - epidemiology
Cohort Studies
Depressive Disorder, Major - epidemiology
Depressive Disorder, Major - psychology
Emotional disorders
Female
Humans
Hypertension - epidemiology
Incidence
major depression
Medical diagnosis
Middle Aged
mood disorders
Myocardial Ischemia - epidemiology
Patients
psycho-oncology
Pulmonary Disease, Chronic Obstructive - epidemiology
Risk Factors
Social support
Taiwan - epidemiology
Young Adult
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Summary:Objective The objective of this study is to assess the incidence and risk of mood disorders, including major depression, anxiety, and bipolar disorders, in Taiwanese patients after the diagnosis of breast cancer compared with a matched cohort. Methods From January 2000 to December 2005, 26,629 newly diagnosed breast cancer patients were enrolled by the Taiwan National Health Insurance program database. The control cohort was selected randomly from 1,000,000 National Health Insurance beneficiaries from a population of 21,400,826 enrolled throughout Taiwan. Each patient was matched with one subject without breast cancer by age, sex, and presence of comorbidities with the same diagnosis index date. The diagnosis of mood disorders was defined by compatible International Classification of Diseases, 9th revision, clinical modification codes plus the prescription of antidepressants for at least 30 days. Results The overall incidence rate ratio of mood disorders was 1.33 (95% CI 1.28–1.39, p 
ISSN:1057-9249
1099-1611
DOI:10.1002/pon.3277