Off-pump no-touch technique: 3-year results compared with the SYNTAX trial

OBJECTIVES A 3-year follow-up of a retrospective, single-centre clinical study of OPCAB (off-pump coronary artery bypass) no-touch technique with arterial composite grafts and an indirect comparison with clinical outcomes of the 3-year follow-up of the SYNTAX trial. METHODS A total of 400 consecutiv...

Full description

Saved in:
Bibliographic Details
Published in:Interactive cardiovascular and thoracic surgery 2015-05, Vol.20 (5), p.601-604
Main Authors: Arrigoni, Sara C., Mecozzi, Gianclaudio, Grandjean, Jan G., Hillege, Jan L., Kappetein, Arie P., Mariani, Massimo A.
Format: Article
Language:English
Subjects:
Aged
Cause of Death
Coronary Angiography - methods
Coronary Artery Bypass, Off-Pump - methods
Coronary Artery Bypass, Off-Pump - mortality
Coronary Stenosis - diagnostic imaging
Coronary Stenosis - mortality
Coronary Stenosis - surgery
Disease-Free Survival
Female
Follow-Up Studies
Hospital Mortality - trends
Humans
Kaplan-Meier Estimate
Length of Stay
Male
Middle Aged
Netherlands
Postoperative Complications - mortality
Postoperative Complications - physiopathology
Risk Assessment
Severity of Illness Index
Stroke - etiology
Stroke - mortality
Survival Rate
Time Factors
Touch
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:OBJECTIVES A 3-year follow-up of a retrospective, single-centre clinical study of OPCAB (off-pump coronary artery bypass) no-touch technique with arterial composite grafts and an indirect comparison with clinical outcomes of the 3-year follow-up of the SYNTAX trial. METHODS A total of 400 consecutive patients (‘all-comers’) who underwent OPCAB no-touch coronary surgery. Primary endpoint was 3-year MACCE (major adverse cardiovascular and cerebrovascular events). These results were compared with the randomized arms of the SYNTAX trial. RESULTS The observed 3-year survival was 82.2%. The cumulative 3-year freedom from MACCE was 89.7%. The percentage of MACCE was significantly lower (P < 0.001) in the OPCAB no-touch group (10.3%) compared with both arms of the SYNTAX trial (20.2 and 28.0%, respectively). Repeat revascularization in the OPCAB no-touch group (4.3%) was significantly lower (P < 0.001) compared with both arms of the SYNTAX trial (10.7 and 19.7%, respectively). The percentage of stroke was significantly lower (P = 0.032) in the OPCAB no-touch group compared with the CABG arm in the SYNTAX trial (1.3 vs 3.4%). There was no significant difference of stroke rate between the OPCAB no-touch group and the PCI arm of the SYNTAX trial (1.3 vs 2%, P = 0.347). CONCLUSIONS The results at the 3-year follow-up showed the safety and efficacy of OPCAB no-touch technique. The OPCAB no-touch technique may improve patients' outcome by minimizing the morbidity and the neurological complications. Prospective controlled trials are needed to confirm these results.
ISSN:1569-9293
1569-9285
DOI:10.1093/icvts/ivv012