Haemato-biochemical Effects of Formulated and Technical Cypermethrin and Deltamethrin Insecticides in Male Rats

Pesticide formulations are complex mixtures and the toxicity information on active ingredients alone is not sufficient to evaluate the risk of adverse health effects of commercial pesticides. So, the present work was conducted to study the haematobiochemical effects of technical and formulated cyper...

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Bibliographic Details
Published in:Journal of pharmacology & toxicology 2012, Vol.7 (7), p.312-321
Main Authors: Abbassy, Moustafa A., H. Mossa, Abdel-Tawab
Format: Article
Language:English
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Summary:Pesticide formulations are complex mixtures and the toxicity information on active ingredients alone is not sufficient to evaluate the risk of adverse health effects of commercial pesticides. So, the present work was conducted to study the haematobiochemical effects of technical and formulated cypermethrin and deltamethrin, in male rats given repetitive oral doses for 90 consecutive days. The partial differences of hematological and biochemical effects obtained with pure and commercial deltamethrin and cypermethrin indicate that commercial formulations may contain additional hazardous compounds. Therefore, it is important in assessing the real human hazard from pesticides to investigate not only the active principle but also the commercial formulations used in agriculture.
ISSN:1816-496X
2152-100X
DOI:10.3923/jpt.2012.312.321