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Australian clinical practice guidelines for the diagnosis and management of Barrett's esophagus and early esophageal adenocarcinoma

Barrett's esophagus (BE), a common condition, is the only known precursor to esophageal adenocarcinoma (EAC). There is uncertainty about the best way to manage BE as most people with BE never develop EAC and most patients diagnosed with EAC have no preceding diagnosis of BE. Moreover, there hav...

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Bibliographic Details
Published in:Journal of gastroenterology and hepatology 2015-05, Vol.30 (5), p.804-820
Main Authors: Whiteman, David C, Appleyard, Mark, Bahin, Farzan F, Bobryshev, Yuri V, Bourke, Michael J, Brown, Ian, Chung, Adrian, Clouston, Andrew, Dickins, Emma, Emery, Jon, Eslick, Guy D, Gordon, Louisa G, Grimpen, Florian, Hebbard, Geoff, Holliday, Laura, Hourigan, Luke F, Kendall, Bradley J, Lee, Eric YT, Levert-Mignon, Angelique, Lord, Reginald V, Lord, Sarah J, Maule, Derek, Moss, Alan, Norton, Ian, Olver, Ian, Pavey, Darren, Raftopoulos, Spiro, Rajendra, Shan, Schoeman, Mark, Singh, Rajvinder, Sitas, Freddy, Smithers, B Mark, Taylor, Andrew C, Thomas, Melissa L, Thomson, Iain, To, Henry, von Dincklage, Jutta, Vuletich, Christine, Watson, David I, Yusoff, Ian F
Format: Article
Language:English
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Summary:Barrett's esophagus (BE), a common condition, is the only known precursor to esophageal adenocarcinoma (EAC). There is uncertainty about the best way to manage BE as most people with BE never develop EAC and most patients diagnosed with EAC have no preceding diagnosis of BE. Moreover, there have been recent advances in knowledge and practice about the management of BE and early EAC. To aid clinical decision making in this rapidly moving field, Cancer Council Australia convened an expert working party to identify pertinent clinical questions. The questions covered a wide range of topics including endoscopic and histological definitions of BE and early EAC; prevalence, incidence, natural history, and risk factors for BE; and methods for managing BE and early EAC. The latter considered modification of lifestyle factors; screening and surveillance strategies; and medical, endoscopic, and surgical interventions. To answer each question, the working party systematically reviewed the literature and developed a set of recommendations through consensus. Evidence underpinning each recommendation was rated according to quality and applicability.
ISSN:0815-9319
1440-1746
DOI:10.1111/jgh.12913