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Enhanced mechanical properties and bone bioactivity of chitosan/silica membrane by functionalized-carbon nanotube incorporation
A space-maintaining ability of degradable guided bone regeneration (GBR) membranes is still a challenge due to weak mechanical strength despite their excellent concept. Here we incorporated functionalized-carbon nanotube (f-CNT) for this purpose. In particular, a hybrid composition of chitosan/silic...
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| Published in: | Composites science and technology 2014-05, Vol.96, p.31-37 |
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| Main Authors: | , , , , , , |
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| cited_by | cdi_FETCH-LOGICAL-c384t-50d5440500df6f1e2eb1ef479b86428ed1f76d1a01b54cebf2b8361e0e1c816c3 |
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| cites | cdi_FETCH-LOGICAL-c384t-50d5440500df6f1e2eb1ef479b86428ed1f76d1a01b54cebf2b8361e0e1c816c3 |
| container_end_page | 37 |
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| container_start_page | 31 |
| container_title | Composites science and technology |
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| creator | Seo, Seog-Jin Kim, Jung-Ju Kim, Joong-Hyun Lee, Ja-Yeon Shin, Ueon Sang Lee, Eun-Jung Kim, Hae-Won |
| description | A space-maintaining ability of degradable guided bone regeneration (GBR) membranes is still a challenge due to weak mechanical strength despite their excellent concept. Here we incorporated functionalized-carbon nanotube (f-CNT) for this purpose. In particular, a hybrid composition of chitosan/silica (CS/Si) was used as the matrix of the GBR membrane. With increasing f-CNT content, hydrophilic nature increased while hydrolytic degradability was reduced. Among the membranes with various contents of f-CNT (up to 3 wt%), 2wt% f-CNT-doped CS/Si showed the highest mechanical properties, including tensile strength and elastic modulus as well as significantly improved bone bioactivity with respect to CS/Si free of f-CNT. In vivo animal study showed favorable tissue responses of the CNT-incorporated membrane. Taken all, the newly-developed CNT/CS/Si may find potential usefulness as a GBR membrane with excellent mechanical properties while exhibiting good bioactivity and tissue reaction. |
| doi_str_mv | 10.1016/j.compscitech.2014.03.004 |
| format | article |
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Here we incorporated functionalized-carbon nanotube (f-CNT) for this purpose. In particular, a hybrid composition of chitosan/silica (CS/Si) was used as the matrix of the GBR membrane. With increasing f-CNT content, hydrophilic nature increased while hydrolytic degradability was reduced. Among the membranes with various contents of f-CNT (up to 3 wt%), 2wt% f-CNT-doped CS/Si showed the highest mechanical properties, including tensile strength and elastic modulus as well as significantly improved bone bioactivity with respect to CS/Si free of f-CNT. In vivo animal study showed favorable tissue responses of the CNT-incorporated membrane. Taken all, the newly-developed CNT/CS/Si may find potential usefulness as a GBR membrane with excellent mechanical properties while exhibiting good bioactivity and tissue reaction.</description><identifier>ISSN: 0266-3538</identifier><identifier>EISSN: 1879-1050</identifier><identifier>DOI: 10.1016/j.compscitech.2014.03.004</identifier><identifier>CODEN: CSTCEH</identifier><language>eng</language><publisher>Kidlington: Elsevier Ltd</publisher><subject>A. Carbon nanotubes ; A. Hybrid composites ; Applied sciences ; B. Mechanical properties ; Biochemistry ; Biological and medical sciences ; Bones ; Chitosan ; Composites ; Degradation ; E. Sol–gel methods ; Exact sciences and technology ; Forms of application and semi-finished materials ; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics ; Maxillofacial surgery. Dental surgery. Orthodontics ; Mechanical properties ; Medical sciences ; Membranes ; Nanostructure ; Polymer industry, paints, wood ; Silicon ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Technology of polymers</subject><ispartof>Composites science and technology, 2014-05, Vol.96, p.31-37</ispartof><rights>2014 Elsevier Ltd</rights><rights>2015 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c384t-50d5440500df6f1e2eb1ef479b86428ed1f76d1a01b54cebf2b8361e0e1c816c3</citedby><cites>FETCH-LOGICAL-c384t-50d5440500df6f1e2eb1ef479b86428ed1f76d1a01b54cebf2b8361e0e1c816c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>315,786,790,27957,27958</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=28433894$$DView record in Pascal Francis$$Hfree_for_read</backlink></links><search><creatorcontrib>Seo, Seog-Jin</creatorcontrib><creatorcontrib>Kim, Jung-Ju</creatorcontrib><creatorcontrib>Kim, Joong-Hyun</creatorcontrib><creatorcontrib>Lee, Ja-Yeon</creatorcontrib><creatorcontrib>Shin, Ueon Sang</creatorcontrib><creatorcontrib>Lee, Eun-Jung</creatorcontrib><creatorcontrib>Kim, Hae-Won</creatorcontrib><title>Enhanced mechanical properties and bone bioactivity of chitosan/silica membrane by functionalized-carbon nanotube incorporation</title><title>Composites science and technology</title><description>A space-maintaining ability of degradable guided bone regeneration (GBR) membranes is still a challenge due to weak mechanical strength despite their excellent concept. Here we incorporated functionalized-carbon nanotube (f-CNT) for this purpose. In particular, a hybrid composition of chitosan/silica (CS/Si) was used as the matrix of the GBR membrane. With increasing f-CNT content, hydrophilic nature increased while hydrolytic degradability was reduced. Among the membranes with various contents of f-CNT (up to 3 wt%), 2wt% f-CNT-doped CS/Si showed the highest mechanical properties, including tensile strength and elastic modulus as well as significantly improved bone bioactivity with respect to CS/Si free of f-CNT. In vivo animal study showed favorable tissue responses of the CNT-incorporated membrane. Taken all, the newly-developed CNT/CS/Si may find potential usefulness as a GBR membrane with excellent mechanical properties while exhibiting good bioactivity and tissue reaction.</description><subject>A. Carbon nanotubes</subject><subject>A. Hybrid composites</subject><subject>Applied sciences</subject><subject>B. Mechanical properties</subject><subject>Biochemistry</subject><subject>Biological and medical sciences</subject><subject>Bones</subject><subject>Chitosan</subject><subject>Composites</subject><subject>Degradation</subject><subject>E. Sol–gel methods</subject><subject>Exact sciences and technology</subject><subject>Forms of application and semi-finished materials</subject><subject>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</subject><subject>Maxillofacial surgery. Dental surgery. Orthodontics</subject><subject>Mechanical properties</subject><subject>Medical sciences</subject><subject>Membranes</subject><subject>Nanostructure</subject><subject>Polymer industry, paints, wood</subject><subject>Silicon</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Technology of polymers</subject><issn>0266-3538</issn><issn>1879-1050</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2014</creationdate><recordtype>article</recordtype><recordid>eNqNkcFu3CAURVHVSJ2m-Qe6qNSNHTAY42U1SpNKkbJJ1wjwQ8PIBheYSNNNf71YE1VZdsXm3Pt45yH0mZKWEipuj62Ny5qtL2APbUcobwlrCeHv0I7KYWwo6cl7tCOdEA3rmfyAPuZ8JIQM_djt0J-7cNDBwoSXWqCDt3rGa4orpOIhYx0mbGIAbHzUtvgXX844OmwPvsSsw232c83U9GKS3rgzdqdQyRj07H_D1FidagMOOsRyMoB9sDGtMemN-YSunJ4z3Ly-1-jn97vn_UPz-HT_Y__tsbFM8tL0ZOo5r6uQyQlHoQNDwfFhNFLwTsJE3SAmqgk1PbdgXGckExQIUCupsOwafb301t1-nSAXtfhsYZ7rn-MpKyoG2lMmRVfR8YLaFHNO4NSa_KLTWVGiNunqqN5IV5t0RZiq0mv2y-sYnatJV5VYn_8VdJIzJseN2184qDu_eEiqtsF2B5_AFjVF_x_T_gJb4KG7</recordid><startdate>20140523</startdate><enddate>20140523</enddate><creator>Seo, Seog-Jin</creator><creator>Kim, Jung-Ju</creator><creator>Kim, Joong-Hyun</creator><creator>Lee, Ja-Yeon</creator><creator>Shin, Ueon Sang</creator><creator>Lee, Eun-Jung</creator><creator>Kim, Hae-Won</creator><general>Elsevier Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7SR</scope><scope>7U5</scope><scope>8FD</scope><scope>JG9</scope><scope>L7M</scope></search><sort><creationdate>20140523</creationdate><title>Enhanced mechanical properties and bone bioactivity of chitosan/silica membrane by functionalized-carbon nanotube incorporation</title><author>Seo, Seog-Jin ; Kim, Jung-Ju ; Kim, Joong-Hyun ; Lee, Ja-Yeon ; Shin, Ueon Sang ; Lee, Eun-Jung ; Kim, Hae-Won</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c384t-50d5440500df6f1e2eb1ef479b86428ed1f76d1a01b54cebf2b8361e0e1c816c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2014</creationdate><topic>A. 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| ispartof | Composites science and technology, 2014-05, Vol.96, p.31-37 |
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| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | A. Carbon nanotubes A. Hybrid composites Applied sciences B. Mechanical properties Biochemistry Biological and medical sciences Bones Chitosan Composites Degradation E. Sol–gel methods Exact sciences and technology Forms of application and semi-finished materials Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics Maxillofacial surgery. Dental surgery. Orthodontics Mechanical properties Medical sciences Membranes Nanostructure Polymer industry, paints, wood Silicon Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Technology of polymers |
| title | Enhanced mechanical properties and bone bioactivity of chitosan/silica membrane by functionalized-carbon nanotube incorporation |
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