Transcriptional Regulation of Glutamic Acid Decarboxylase in the Male Mouse Amygdala by Dietary Phyto-Oestrogens

Phyto‐oestrogens are biologically active components of many human and laboratory animal diets. In the present study, we investigated, in adult male mice with C57BL/6 genetic background, the effects of a reduced phyto‐oestrogens intake on anxiety‐related behaviour and associated gene expression in th...

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Bibliographic Details
Published in:Journal of neuroendocrinology 2015-04, Vol.27 (4), p.285-292
Main Authors: Sandhu, K. V., Yanagawa, Y., Stork, O.
Format: Article
Language:English
Subjects:
Amygdala - drug effects
Amygdala - enzymology
Amygdala - metabolism
Animals
anxiety
Anxiety - genetics
Anxiety - metabolism
basolateral amygdala
Behavior, Animal - drug effects
Diet
gene expression
Gene Expression Regulation, Enzymologic - drug effects
Glutamate Decarboxylase - genetics
Glutamate Decarboxylase - metabolism
glutamic acid decarboxylase
Male
male mice
Mice
Mice, Inbred C57BL
Mice, Transgenic
neuropeptide Y
Neuropeptide Y - genetics
Neuropeptide Y - metabolism
Phyto-oestrogens
Phytoestrogens - pharmacology
Transcription, Genetic - drug effects
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Summary:Phyto‐oestrogens are biologically active components of many human and laboratory animal diets. In the present study, we investigated, in adult male mice with C57BL/6 genetic background, the effects of a reduced phyto‐oestrogens intake on anxiety‐related behaviour and associated gene expression in the amygdala. After 6 weeks on a low‐phyto‐oestrogen diet (
ISSN:0953-8194
1365-2826
DOI:10.1111/jne.12262