Immune Responses to Pollutant Mixtures from Indoor Sources

Indoor air pollution occurs as an undesirable consequence of urbanization, energy conservation, indoor bioaerosol contamination, and use of synthetic materials and new technologies, and has become a worldwide concern. It is important to comprehend not only the diversity of pollutant hazards but also...

Full description

Saved in:
Bibliographic Details
Published in:ANNALS OF THE NEW YORK ACADEMY OF SCIENCES-SERIES 1992-04, Vol.641 (1), p.199-214
Main Authors: BROOKS, BRADFORD O., ALDRICH, FRANKLIN D., UTTER, GARY M., DeBROY, JAMES A., SCHIMKE, ROGER D.
Format: Article
Language:English
Subjects:
Air Pollution, Indoor - adverse effects
Animals
Humans
Hypersensitivity - diagnosis
Hypersensitivity - immunology
Multidisciplinary Sciences
Research Design
Science & Technology
Science & Technology - Other Topics
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Indoor air pollution occurs as an undesirable consequence of urbanization, energy conservation, indoor bioaerosol contamination, and use of synthetic materials and new technologies, and has become a worldwide concern. It is important to comprehend not only the diversity of pollutant hazards but also to develop novel methods and approaches that establish dose-response relationships, cause-and-effect relationships, and clinical relevance. Coincident with heightened public concern over indoor air pollution and its health consequences, a revolution in immunology has occurred. The immune system is recognized as an essential defensive and homeostatic mechanism. Unfortunately, the immune apparatus is exquisitely sensitive to toxic damage. Equally important, among the disciplines available to assess the health impact of indoor air pollutants, immunology has the capability to provide sensitive and specific tools that may accurately measure relevant clinical effects at tissue, cellular, and molecular levels. Furthermore, exciting new insights into shared communications networks between the immune, endocrine, and central nervous systems may provide future explanations for the myriad human complaints associated with indoor air pollutants.
ISSN:0077-8923
1749-6632
DOI:10.1111/j.1749-6632.1992.tb16544.x