Hypochromic vitiligo: delineation of a new entity

Summary Background Hypochromic vitiligo is a rare entity that has been reported only twice under the term ‘vitiligo minor’, with an absence of clear delineation. Objectives To delineate hypochromic vitiligo through a case series of patients with typical bilateral hypopigmented lesions affecting the...

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Bibliographic Details
Published in:British journal of dermatology (1951) 2015-03, Vol.172 (3), p.716-721
Main Authors: Ezzedine, K., Mahé, A., van Geel, N., Cardot-Leccia, N., Gauthier, Y., Descamps, V., Al Issa, A., Ly, F., Chosidow, O., Taïeb, A., Passeron, T.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Child
Facial Dermatoses - classification
Facial Dermatoses - pathology
Female
Humans
Male
Middle Aged
Retrospective Studies
Torso
Vitiligo - classification
Vitiligo - pathology
Young Adult
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Summary:Summary Background Hypochromic vitiligo is a rare entity that has been reported only twice under the term ‘vitiligo minor’, with an absence of clear delineation. Objectives To delineate hypochromic vitiligo through a case series of patients with typical bilateral hypopigmented lesions affecting the face and trunk. Methods This is a retrospective multicentric evaluation study conducted in eight departments of dermatology in France, Belgium, Senegal and Saudi Arabia. Results Twenty‐four cases of hypochromic vitiligo were identified. Fourteen were men and 10 women. The mean age at diagnosis was 35·4 years (range 8–66). Strikingly, all patients were dark skinned, with skin types V and VI. The pattern of distribution was highly similar in most of the patients (18 of 24), with involvement of the face and neck area predominating on seborrhoeic areas associated with multiple isolated hypopigmented macules involving predominantly the scalp. The retrospective nature of this study is its main limitation. Conclusions Hypochromic vitiligo is not yet part of a conventional classification. The disease seems to be limited to individuals with dark skin types. Hypopigmented seborrhoeic face and neck involvement associated with hypopigmented macules of the trunk and scalp is the hallmark of the disease. What's already known about this topic? The classification of vitiligo has important implications. Few observations of vitiligo minor/hypochromic vitiligo, a rare entity affecting mainly individuals with dark skin types, have been reported. What does this study add? We herein delineate a new entity that we called ‘hypochromic vitiligo’ through a case series of 24 patients with typical clinical presentation.
ISSN:0007-0963
1365-2133
DOI:10.1111/bjd.13423