Cognitive function and health-related quality of life four years after cardiac arrest

Abstract Aim Neuropsychological testing has uncovered cognitive impairment in cardiac arrest survivors with good neurologic outcome according to the cerebral performance categories. We investigated cognitive function and health-related quality of life four years after cardiac arrest. Methods Thirty...

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Bibliographic Details
Published in:Resuscitation 2015-04, Vol.89, p.13-18
Main Authors: Buanes, Eirik Alnes, Gramstad, Arne, Søvig, Karoline Kjellsdotter, Hufthammer, Karl Ove, Flaatten, Hans, Husby, Thomas, Langørgen, Jørund, Heltne, Jon-Kenneth
Format: Article
Language:English
Subjects:
Aged
CANTAB
Cardiac arrest
Cardiopulmonary Resuscitation
Case-Control Studies
Cognition disorders
Cognition Disorders - epidemiology
Cohort Studies
Critical Care
Emergency
Female
Health Status
Heart Arrest - complications
Heart Arrest - psychology
Heart Arrest - therapy
Humans
Hypothermia, Induced
Length of Stay
Male
Middle Aged
Neuropsychological Tests
Norway
Quality of life
Quality of Life - psychology
Time Factors
Treatment outcome
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Summary:Abstract Aim Neuropsychological testing has uncovered cognitive impairment in cardiac arrest survivors with good neurologic outcome according to the cerebral performance categories. We investigated cognitive function and health-related quality of life four years after cardiac arrest. Methods Thirty cardiac arrest survivors over the age of 18 in cerebral performance category 1 or 2 on hospital discharge completed the EQ-5D-5L and HADS questionnaires prior to cognitive testing using the Cambridge Neuropsychological Test Automated Battery. The results were compared with population norms. Results Twenty-nine per cent of patients were cognitively impaired. The pattern of cognitive impairment reflects dysfunction in the medial temporal lobe, with impaired short-time memory and executive function slightly but distinctly affected. There was a significant reduction in quality of life on the EQ-VAS, but not on the EQ index. Conclusion Cognitive impairment four years after cardiac arrest affected more than one quarter of the patients. Short-term memory was predominantly affected.
ISSN:0300-9572
1873-1570
DOI:10.1016/j.resuscitation.2014.12.021