Accumulation of PHA and its copolyesters by Methylobacterium sp. KCTC 0048

Methylobacterium sp. KCTC 0048 isolated from soil, could synthesize a variety of copolyesters when secondary carbon substrates were added to nitrogen-limited cultures containing methanol as a major carbon and energy source. The copolyester of 3-hydroxybutyrate and 3-hydroxyvalerate, P(3HB-co-3HV) ac...

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Bibliographic Details
Published in:Biotechnology letters 1993-10, Vol.15 (10), p.1017-1020
Main Authors: Kang, C.K, Lee, H.S, Kim, J.H
Format: Article
Language:English
Subjects:
ammonium compounds
Biological and medical sciences
Biology of microorganisms of confirmed or potential industrial interest
biosynthesis
Biotechnology
fermentation
Fundamental and applied biological sciences. Psychology
methanol
Methylobacterium
methylotrophic bacteria
microbial polyesters
Mission oriented research
nutrient deficiencies
Physiology and metabolism
polyesters
polyhydroxyalkanoate
secondary carbon substrates
soil bacteria
substrates
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Summary:Methylobacterium sp. KCTC 0048 isolated from soil, could synthesize a variety of copolyesters when secondary carbon substrates were added to nitrogen-limited cultures containing methanol as a major carbon and energy source. The copolyester of 3-hydroxybutyrate and 3-hydroxyvalerate, P(3HB-co-3HV) accumulated when valeric acid, pentanol or heptanoic acid was added to the nitrogen-limited medium containing methanol. The copolyester of 3-hydroxybutyrate and 4-hydroxybutyrate, P(3HB-co-4HB) was synthesized from 4-hydroxybutyrate, 1,4-butanediol, or gamma-butyrolactone, and the copolyester of 3-hydroxybutyrate and 3-hydroxypropionate P(3HB-co-3HP)), from 3-hydroxypropionate as the secondary carbon substrates, respectively.
ISSN:0141-5492
1573-6776
DOI:10.1007/BF00129929