The effects of metabolic syndrome and its components on arterial stiffness in relation to gender

Abstract Objectives The influence of gender-dependent metabolic risk factors on arterial stiffness has not been fully determined. This study was performed to investigate the relationship between components of metabolic syndrome and brachial-ankle pulse wave velocity (baPWV) according to gender. Meth...

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Bibliographic Details
Published in:Journal of cardiology 2015-03, Vol.65 (3), p.243-249
Main Authors: Kim, Hack-Lyoung, MD, PhD, Lee, Ju-Myung, MD, Seo, Jae-Bin, MD, PhD, Chung, Woo-Young, MD, PhD, Kim, Sang-Hyun, MD, PhD, Zo, Joo-Hee, MD, PhD, Kim, Myung-A, MD, PhD
Format: Article
Language:English
Subjects:
Adult
Aged
Ankle - blood supply
Arterial stiffness
Blood Glucose - analysis
Blood Pressure - physiology
Brachial Artery
Brachial-ankle pulse wave velocity
Cardiovascular
Fasting - blood
Female
Gender
Humans
Lipoproteins, HDL - blood
Male
Metabolic syndrome
Metabolic Syndrome - blood
Metabolic Syndrome - physiopathology
Middle Aged
Pulse Wave Analysis - methods
Risk Factors
Sex Factors
Triglycerides - blood
Vascular Stiffness - physiology
Waist Circumference
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Summary:Abstract Objectives The influence of gender-dependent metabolic risk factors on arterial stiffness has not been fully determined. This study was performed to investigate the relationship between components of metabolic syndrome and brachial-ankle pulse wave velocity (baPWV) according to gender. Methods A total of 537 subjects (54.4 ± 7.5 years and 70.6% men) who underwent baPWV measurement during routine check-ups were analyzed. Results BaPWV was 1363 ± 229 cm/s in men and 1387 ± 269 cm/s in women ( p = 0.313). The prevalence of metabolic syndrome was not different according to gender (23% in men versus 27% in women, p = 0.335). In multiple linear regression analyses, after adjustment for age, baPWV was significantly associated with systolic and diastolic blood pressures, fasting glucose, and triglyceride in both genders. Waist circumference was associated with baPWV in women but not in men. High-density lipoprotein levels were not associated with baPWV in either gender. Subjects with metabolic syndrome had a higher baPWV than those without metabolic syndrome for women aged
ISSN:0914-5087
1876-4738
DOI:10.1016/j.jjcc.2014.05.009