New tetrahydroimidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-one and -thione derivatives are potent inhibitors of human immunodeficiency virus type 1 replication and are synergistic with 2',3'-dideoxynucleoside analogs

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Published in:Antimicrobial Agents and Chemotherapy 1994-12, Vol.38 (12), p.2863-2870
Main Authors: PAUWELS, R, ANDRIES, K, JANSSEN, P. A. J, DEBYSER, Z, KUKLA, M. J, SCHOLS, D, BRESLIN, H. J, WOESTENBORGHS, R, DESMYTER, J, JANSSEN, M. A. C, DE CLERCQ, E
Format: Article
Language:English
Subjects:
Antibiotics. Antiinfectious agents. Antiparasitic agents
Antiviral Agents
Antiviral Agents - pharmacology
Benzodiazepines
Benzodiazepines - pharmacology
Biological and medical sciences
Didanosine
Didanosine - pharmacology
Drug Synergism
HIV Reverse Transcriptase
HIV-1
HIV-1 - drug effects
human immunodeficiency virus 1
Imidazoles - pharmacology
Medical sciences
Pharmacology. Drug treatments
Research Article
Reverse Transcriptase Inhibitors
Structure-Activity Relationship
Virus Replication
Virus Replication - drug effects
Zidovudine
Zidovudine - pharmacology
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Summary:Classifications Services AAC Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit StumbleUpon Twitter current issue AAC About AAC Subscribers Authors Reviewers Advertisers Inquiries from the Press Permissions & Commercial Reprints ASM Journals Public Access Policy AAC RSS Feeds 1752 N Street N.W. • Washington DC 20036 202.737.3600 • 202.942.9355 fax • journals@asmusa.org Print ISSN: 0066-4804 Online ISSN: 1098-6596 Copyright © 2014 by the American Society for Microbiology.   For an alternate route to AAC .asm.org, visit: AAC       
ISSN:0066-4804
1098-6596
DOI:10.1128/AAC.38.12.2863