Quantitative EEG markers relate to Alzheimer’s disease severity in the Prospective Dementia Registry Austria (PRODEM)

Highlights • Largest clinical study of quantitative EEG markers for slowing, synchrony and complexity versus AD severity including 118 patients. • Advanced metrics for quantitative EEG in resting state and during a face–name encoding task. • MMSE scores explaining up to 51% of the variations in QEEG...

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Bibliographic Details
Published in:Clinical neurophysiology 2015-03, Vol.126 (3), p.505-513
Main Authors: Garn, Heinrich, Waser, Markus, Deistler, Manfred, Benke, Thomas, Dal-Bianco, Peter, Ransmayr, Gerhard, Schmidt, Helena, Sanin, Guenter, Santer, Peter, Caravias, Georg, Seiler, Stephan, Grossegger, Dieter, Fruehwirt, Wolfgang, Schmidt, Reinhold
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Alzheimer Disease - diagnosis
Alzheimer Disease - physiopathology
Alzheimer’s disease
Austria
Biomarkers
Brain - physiopathology
Electroencephalography
Female
Humans
Male
Middle Aged
Neurology
Neuropsychological Tests
PRODEM
Prospective Studies
Quantitative electroencephalogram
Registries
Severity of Illness Index
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Summary:Highlights • Largest clinical study of quantitative EEG markers for slowing, synchrony and complexity versus AD severity including 118 patients. • Advanced metrics for quantitative EEG in resting state and during a face–name encoding task. • MMSE scores explaining up to 51% of the variations in QEEG markers.
ISSN:1388-2457
1872-8952
DOI:10.1016/j.clinph.2014.07.005