Kidney Transplantation With Organs From Donors After Circulatory Death Type 3: A Prospective Multicentric Spanish Study (GEODAS 3)

Abstract To increase the number of kidney donors, new strategies are needed such as living donor programs, expanded criteria donors, or donors after circulatory death (DCD) kidney transplantation programs. The GEODAS group has started an observational, prospective, multicenter clinical study, collec...

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Bibliographic Details
Published in:Transplantation proceedings 2015, Vol.47 (1), p.27-29
Main Authors: Portolés Pérez, J, Lafuente, O, Sánchez-Sobrino, B, Pérez Sáez, M.J, Fernández García, A, Llamas, F, López-Sánchez, P, Rodriguez-Ferrero, M.L, Zarraga, S, Ramos, A, Pascual, J
Format: Article
Language:English
Subjects:
Adult
Aged
Creatinine
Death
Delayed Graft Function - epidemiology
Donor Selection
Female
Graft Survival
Humans
Kidney Failure, Chronic - mortality
Kidney Failure, Chronic - surgery
Kidney Transplantation
Male
Middle Aged
Prospective Studies
Shock
Spain
Surgery
Treatment Outcome
Young Adult
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Summary:Abstract To increase the number of kidney donors, new strategies are needed such as living donor programs, expanded criteria donors, or donors after circulatory death (DCD) kidney transplantation programs. The GEODAS group has started an observational, prospective, multicenter clinical study, collecting data from all DCD type-3 kidney transplantations performed in seven Spanish hospitals from January 2012 to January 2014. The preliminary results have shown a delayed graft function of 40.4% and graft survival of 93.7% with a nadir creatinine of 1.3 mg/dL. From all 33 potential donors included in the study, 32 were effective and 63 kidney grafts were transplanted with a utilization rate of 98.5%. Creatinine evolution (median [range]) was in the first month: 2.1 [0.6–5.6]; third month: 1.6 [0.8, 4.2]; first year: 1.6 [0.9–2.2]. These results are similar to kidney transplantation from donors after brain death as shown in the literature, especially in the graft and recipient survival rates. In addition, the controlled programs are easier and less expensive than uncontrolled DCD programs with a higher rate of graft use.
ISSN:0041-1345
1873-2623
DOI:10.1016/j.transproceed.2014.12.008