Global Surgical Oncology Disease Burden: Addressing Disparities Via Global Surgery Initiatives: The University of Michigan International Breast Cancer Registry

Global Surgical Oncology Disease Burden: Addressing Disparities Via Global Surgery Initiatives: The University of Michigan International Breast Cancer Registry

Background Disparities in breast cancer incidence and outcome between African American and white American women are multifactorial in etiology. The increased frequency of triple-negative breast cancers (TNBC) in African American patients suggests the possible contribution of hereditary factors relat...

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Bibliographic Details
Published in:Annals of surgical oncology 2015-03, Vol.22 (3), p.734-740
Main Authors: Jiagge, Evelyn, Bensenhaver, Jessica M., Oppong, Joseph K., Awuah, Baffour, Newman, Lisa A.
Format: Article
Language:eng
Subjects:
Breast Neoplasms - ethnology
Breast Neoplasms - pathology
Breast Neoplasms - surgery
Breast Oncology
Ethnic Groups - statistics & numerical data
Female
Humans
Incidence
International Agencies
Medical Oncology
Medicine
Medicine & Public Health
Oncology
Prognosis
Registries
Specialties, Surgical
Surgery
Surgical Oncology
Tumor Burden
Universities
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Summary:Background Disparities in breast cancer incidence and outcome between African American and white American women are multifactorial in etiology. The increased frequency of triple-negative breast cancers (TNBC) in African American patients suggests the possible contribution of hereditary factors related to African ancestry. Methods The University of Michigan (UM)-Komfo Anoyke Teaching Hospital (KATH) Breast Cancer Research Collaborative and International Breast Registry was established in 2004. It features epidemiologic information, tumor tissue, and germline DNA specimens from African American, white American, and Ghanaian women. Results This research collaborative has generated valuable findings regarding the pathogenesis and patterns of TNBC while concomitantly improving the standard of breast oncology care in Ghana. This partnership has also yielded important opportunities for academic and educational exchange. It has expanded to involve other sites in Africa and Haiti. Conclusions The UM-KATH collaborative is a model for demonstrating the research and academic exchange value of international partnerships.
ISSN:1068-9265
1534-4681