Sepsis in diabetes: A bad duo

Highlights ► Infection related morbidity and mortality is higher in diabetes. ► Significant factors are hyperglycemia, circulatory abnormality and poor immunity. ► Cytokine dysregulation plays vital role & therapy against this may be beneficial. ► Early and accurate diagnosis of infection help i...

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Bibliographic Details
Published in:Diabetes & metabolic syndrome clinical research & reviews 2011-10, Vol.5 (4), p.222-227
Main Authors: Tiwari, Shalbha, Pratyush, D. Devi, Gahlot, Ankur, Singh, Surya K
Format: Article
Language:English
Subjects:
Cytokine dysregulation
Diabetes mellitus
Diabetes Mellitus - physiopathology
Diabetic foot
Endocrinology & Metabolism
Humans
Hyperglycemia - physiopathology
Hypoglycemia - physiopathology
Infection
Prognosis
Sepsis
Sepsis - physiopathology
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Summary:Highlights ► Infection related morbidity and mortality is higher in diabetes. ► Significant factors are hyperglycemia, circulatory abnormality and poor immunity. ► Cytokine dysregulation plays vital role & therapy against this may be beneficial. ► Early and accurate diagnosis of infection help in proper antibiotic selection. ► Insulin infusion protocols with low chance of hypoglycemia are recommended.
ISSN:1871-4021
1878-0334
DOI:10.1016/j.dsx.2012.02.026