Low-technology assisted reproduction and the risk of preterm birth in a hospital-based cohort

Objective To estimate the risk of preterm birth in singleton infants conceived through low-technology assisted reproduction (intrauterine insemination and/or ovulation induction/stimulation). Design Hospital-based cohort study. Setting University-affiliated hospital. Patient(s) Singleton babies born...

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Bibliographic Details
Published in:Fertility and sterility 2015, Vol.103 (1), p.81-88.e2
Main Authors: Messerlian, Carmen, Ph.D, Platt, Robert W., Ph.D, Tan, Seang-Lin, M.D, Gagnon, Robert, M.D, Basso, Olga, Ph.D
Format: Article
Language:English
Subjects:
Assisted reproduction
Causality
Cohort Studies
Female
Hospitalization - statistics & numerical data
Humans
Incidence
infertility
Infertility - epidemiology
Infertility - therapy
Insemination, Artificial - statistics & numerical data
Internal Medicine
intrauterine insemination
Obstetrics and Gynecology
ovulation induction
Ovulation Induction - statistics & numerical data
Pregnancy
Pregnancy Outcome - epidemiology
Premature Birth - epidemiology
preterm birth
Quebec - epidemiology
Risk Factors
Treatment Outcome
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Summary:Objective To estimate the risk of preterm birth in singleton infants conceived through low-technology assisted reproduction (intrauterine insemination and/or ovulation induction/stimulation). Design Hospital-based cohort study. Setting University-affiliated hospital. Patient(s) Singleton babies born between 2001 and 2007 to 16,712 couples with no reported infertility (reference category), 378 babies conceived with low-technology treatment; 437 conceived with high-technology treatment; and 620 conceived naturally after a period of infertility. Intervention(s) None. Treatment data were obtained from couples undergoing standard infertility investigation and care. Main Outcome Measure(s) Preterm birth, defined at three clinical endpoints:
ISSN:0015-0282
1556-5653
DOI:10.1016/j.fertnstert.2014.10.006