Patterns of increases in interleukin-6 and C-reactive protein as predictors for white matter injury in preterm infants

Background The aim of this study was to determine whether patterns of increases in serum interleukin‐6 (IL‐6) and C‐reactive protein (CRP) levels at birth were associated with the development of white matter injury (WMI) in preterm infants with a fetal inflammatory response (FIR). Methods One hundre...

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Bibliographic Details
Published in:Pediatrics international 2014-12, Vol.56 (6), p.851-855
Main Authors: Inomata, Kei, Mizobuchi, Masami, Tanaka, Satoshi, Iwatani, Sota, Sakai, Hitomi, Yoshimoto, Seiji, Nakao, Hideto
Format: Article
Language:English
Subjects:
C-reactive protein
C-Reactive Protein - metabolism
Chorioamnionitis - blood
Chorioamnionitis - diagnosis
Cytokines
Drug therapy
Female
Humans
Infant, Newborn
Infant, Premature
Infant, Premature, Diseases - blood
Infant, Premature, Diseases - diagnosis
interleukin-6
Interleukin-6 - blood
Leukomalacia, Periventricular - blood
Leukomalacia, Periventricular - diagnosis
Male
Neurology
Pediatrics
periventricular leukomalacia
Pregnancy
Premature birth
premature infant
Proteins
Retrospective Studies
White Matter - injuries
white matter injury
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Summary:Background The aim of this study was to determine whether patterns of increases in serum interleukin‐6 (IL‐6) and C‐reactive protein (CRP) levels at birth were associated with the development of white matter injury (WMI) in preterm infants with a fetal inflammatory response (FIR). Methods One hundred infants who were born at
ISSN:1328-8067
1442-200X
DOI:10.1111/ped.12376