Facile preparation of surface N-halamine chitin nanofiber to endow antibacterial and antifungal activities

•N-halamine chitin nanofiber was prepared by reaction with sodium hypochlorite.•Active chlorine content depended on the NaClO concentration and reaction time.•N-Chlorination reaction took place at the surface of nanofibers.•Chlorine was rechargeable by another treatment.•The material showed strong e...

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Bibliographic Details
Published in:Carbohydrate polymers 2015-01, Vol.115, p.342-347
Main Authors: Dutta, A.K., Egusa, M., Kaminaka, H., Izawa, H., Morimoto, M., Saimoto, H., Ifuku, S.
Format: Article
Language:English
Subjects:
Alternaria - drug effects
Alternaria alternata
Anti-bacterial
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
Anti-fungal
Antifungal Agents - chemistry
Antifungal Agents - pharmacology
Chitin
Chitin - chemistry
Chitin - pharmacology
Escherichia coli
Escherichia coli - drug effects
Microbial Sensitivity Tests
N-halamine
Nanofibers
Nanofibers - chemistry
Penicillium - drug effects
Penicillium digitatum
Staphylococcus aureus
Staphylococcus aureus - drug effects
Surface Properties
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Summary:•N-halamine chitin nanofiber was prepared by reaction with sodium hypochlorite.•Active chlorine content depended on the NaClO concentration and reaction time.•N-Chlorination reaction took place at the surface of nanofibers.•Chlorine was rechargeable by another treatment.•The material showed strong efficacies against bacteria and fungi. N-halamine chitin nanofiber (NF) film was prepared by the reaction of chitin NF film with sodium hypochlorite solution to endow the film with antibacterial and antifungal activities. The amount of active chlorine content loaded on the chitin NF film depended on the sodium hypochlorite concentration and reaction time. FT-IR, UV–vis, XRD, and TG analyses showed that the NH bond was substituted to the NCl bond and that the reaction took place at the chitin NF surface. After chlorination, the characteristic nanochitin morphology was maintained. Although the active chlorine content of the film gradually decreased by disassociation of the NCl bond, chlorine was rechargeable into chitin NF by another sodium hypochlorite solution treatment. The chlorinated chitin NF film showed strong efficacies against Gram-negative and -positive bacteria of Escherichia coli and Staphylococcus aureus, respectively. Moreover, the films showed 100% and 80% inhibition of spore germination when faced against Alternaria alternata and Penicillium digitatum fungi, respectively.
ISSN:0144-8617
1879-1344
DOI:10.1016/j.carbpol.2014.08.094