Production of microparticles with gelatin and chitosan

•Microparticles could be prepared when chitosan was protonated before complexing with gelatin.•TPP-cross-linked microparticles resisted spray drying.•Glu-cross-linked microparticles grouped after drying. In the past few decades, the textile industry has significantly increased investment in research...

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Bibliographic Details
Published in:Carbohydrate polymers 2015-02, Vol.116, p.292-299
Main Authors: Prata, A.S., Grosso, C.R.F.
Format: Article
Language:English
Subjects:
Chitosan
Chitosan - chemistry
Complex coacervation
Cross-Linking Reagents - chemistry
Gelatin - chemistry
Glutaral - chemistry
Limonene
Particle Size
Polyphosphates - chemistry
Spray drying
Tripolyphosphate
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Summary:•Microparticles could be prepared when chitosan was protonated before complexing with gelatin.•TPP-cross-linked microparticles resisted spray drying.•Glu-cross-linked microparticles grouped after drying. In the past few decades, the textile industry has significantly increased investment in research to develop functional fabrics, with a special focus on those aggregating values. Such fabrics can exploit microparticles inferior to 100μm, such as those made by complex coacervation in their creation. The antimicrobial properties of chitosan can be attributed to these microparticles. Developing particles with uniform structure and properties would facilitate the control for the eventual release of the core material. Thus, a complex coacervation between gelatin and chitosan was studied, and the optimal conditions were replicated in the encapsulation of limonene. Spherical particles formed had an average diameter (D3,2) of 30μm and were prepared with 89.7% efficiency. Cross-linking of these microparticles using glutaraldehyde and tripolyphosphate was carried out before spray drying. After drying, microparticles cross-linked with glutaraldehyde were oxidized and clustered and those that were cross-linked with tripolyphosphate resisted drying and presented a high yield.
ISSN:0144-8617
1879-1344
DOI:10.1016/j.carbpol.2014.03.056