Indirect application of near infrared light induces neuroprotection in a mouse model of parkinsonism – An abscopal neuroprotective effect

Highlights • Near infrared light (NIr), directed transcranially, is neuroprotective in rodent models of neurodegeneration. • We assessed the neuroprotective efficacy of remotely-applied NIr in an MPTP mouse model of parkinsonism. • As with transcranial NIr, remote NIr protects dopaminergic cells fro...

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Bibliographic Details

Published in:	Neuroscience 2014-08, Vol.274, p.93-101
Main Authors:	Johnstone, D.M, el Massri, N, Moro, C, Spana, S, Wang, X.S, Torres, N, Chabrol, C, De Jaeger, X, Reinhart, F, Purushothuman, S, Benabid, A.-L, Stone, J, Mitrofanis, J
Format:	Article
Language:	eng
Subjects:	Animals Astrocytes - metabolism Biological and medical sciences Cell Count Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Disease Models, Animal Male Medical sciences Mice Mice, Inbred BALB C Microglia - metabolism mouse model MPTP near infrared light Nervous system (semeiology, syndromes) Nervous system as a whole Neurology neuroprotection Neuroprotective Agents Parkinsonian Disorders - metabolism Parkinsonian Disorders - therapy Parkinson’s disease Pars Compacta - metabolism Phototherapy Tyrosine 3-Monooxygenase - metabolism
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