Individual Patient Data Meta-Analysis Is Needed in Chinese Medical Research

Publication biases and collection limitations are the main disadvantages of a traditional meta-analysis based on aggregate patient data（APD）from published articles.Individual patient data（IPD）meta-analysis,as the gold standard of systematic review,is a possible alternative in this context.However,th...

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Bibliographic Details
Published in:Chinese journal of integrative medicine 2014-11, Vol.20 (11), p.805-811
Main Author: 闫世艳 何丽云 刘保延
Format: Article
Language:English
Subjects:
APD
Biomedical Research
Feature Article
Humans
IPD
Medicine
Medicine & Public Health
Meta分析
Patients
中国医药
功能说明
医学
患者
研究人员
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Summary:Publication biases and collection limitations are the main disadvantages of a traditional meta-analysis based on aggregate patient data（APD）from published articles.Individual patient data（IPD）meta-analysis,as the gold standard of systematic review,is a possible alternative in this context.However,the publications relative to IPD meta-analyses are still rare compared with the traditional ones,especially in the research oriented to Chinese medicine（CM）.In this article,the strengths and detailed functioning of IPD meta-analysis are described.Furthermore,the need for IPD meta-analysis to assess the treatments based on CM was also discussed.Compared with the traditional APD meta-analysis,the IPD meta-analysis might give a more accurate and unbiased assessment and is worth to be recommended to CM researchers.
ISSN:1672-0415
1993-0402
DOI:10.1007/s11655-014-1852-0