Select critically ill patients at risk of augmented renal clearance: experience in a Malaysian intensive care unit

Augmented renal clearance (ARC) refers to increased solute elimination by the kidneys. ARC has considerable implications for altered drug concentrations. The aims of this study were to describe the prevalence of ARC in a select cohort of patients admitted to a Malaysian intensive care unit (ICU) and...

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Bibliographic Details
Published in:Anaesthesia and intensive care 2014-11, Vol.42 (6), p.715-722
Main Authors: Adnan, S, Ratnam, S, Kumar, S, Paterson, D, Lipman, J, Roberts, J, Udy, A A
Format: Article
Language:English
Subjects:
Adult
Cohort Studies
Creatinine - blood
Creatinine - urine
Critical Illness
Female
Glomerular Filtration Rate - physiology
Humans
Inpatients - statistics & numerical data
Intensive Care Units - statistics & numerical data
Kidney - physiopathology
Kidney Function Tests - methods
Kidney Function Tests - statistics & numerical data
Malaysia
Male
Middle Aged
Risk Factors
Young Adult
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Summary:Augmented renal clearance (ARC) refers to increased solute elimination by the kidneys. ARC has considerable implications for altered drug concentrations. The aims of this study were to describe the prevalence of ARC in a select cohort of patients admitted to a Malaysian intensive care unit (ICU) and to compare measured and calculated creatinine clearances in this group. Patients with an expected ICU stay of
ISSN:0310-057X
1448-0271
DOI:10.1177/0310057x1404200606