Prevalence and risk factors associated with low-impact fractures in men with rheumatoid arthritis

The aim of this study is to describe the prevalence of fractures in men with rheumatoid arthritis (RA) and identify potential risk factors associated with skeletal fragility. We consecutively studied 50 men with RA. Clinical risk factors were evaluated by clinical questionnaire, functional capacity...

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Bibliographic Details
Published in:Clinical rheumatology 2014-10, Vol.33 (10), p.1389-1395
Main Authors: Filho, José Carlos Amaral, Pinheiro, Marcelo Medeiros, de Moura Castro, Charlles Heldan, Szejnfeld, Vera Lúcia
Format: Article
Language:English
Subjects:
Adult
Aged
Arthritis, Rheumatoid - complications
Arthritis, Rheumatoid - physiopathology
Bone Density - physiology
Calcaneus - diagnostic imaging
Case-Control Studies
Humans
Logistic Models
Lumbar Vertebrae - injuries
Male
Medicine
Medicine & Public Health
Middle Aged
Original Article
Prevalence
Rheumatology
Risk Factors
Severity of Illness Index
Spinal Fractures - epidemiology
Spinal Fractures - physiopathology
Surveys and Questionnaires
Thoracic Vertebrae - injuries
Ultrasonography
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Summary:The aim of this study is to describe the prevalence of fractures in men with rheumatoid arthritis (RA) and identify potential risk factors associated with skeletal fragility. We consecutively studied 50 men with RA. Clinical risk factors were evaluated by clinical questionnaire, functional capacity by M-HAQ1, and disease activity by DAS-28. RA men were compared to 52 healthy controls paired for age and BMI. Bone mineral density (BMD) and quantitative ultrasound (QUS) at the heel were performed in all participants. Morphometric vertebral fractures (VF) were classified by a semiquantitative method. Men with RA were 51.7 years old on average and had mean disease duration of 115 months. Fragility fractures were found in 40 % of individuals, of which 36 % were VF, significantly higher than in healthy controls ( p  
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-013-2426-9