Association of FEV sub(1) in Asthmatic Children with Personal and Microenvironmental Exposure to Airborne Particulate Matter

Measurements of hourly personal particulate matter (PM) and stationary-site 24-h average PM sub(2.5) were used to evaluate the relationship of repeated measurements of forced expiratory volume in 1 s (FEV sub(1)) in asthmatic children with fine particle exposure. The study was conducted in Alpine, C...

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Bibliographic Details
Published in:Environmental health perspectives 2004-06, Vol.112 (8), p.932-932
Main Authors: Delfino, Ralph J, Quintana, Penelope JE, Floro, Josh, Gastanaga, Victor M, Samimi, Behzad S, Kleinman, Michael T, Liu, L-JSally
Format: Article
Language:English
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Summary:Measurements of hourly personal particulate matter (PM) and stationary-site 24-h average PM sub(2.5) were used to evaluate the relationship of repeated measurements of forced expiratory volume in 1 s (FEV sub(1)) in asthmatic children with fine particle exposure. The study was conducted in Alpine, CA, which receives long-range-transported air pollution from Los Angeles and San Diego. An inverse association was found between percent predicted FEV sub(1) and personal exposure to fine particles, and the magnitudes of the associations were, in some cases, clinically relevant. Inverse associations were also found for FEV sub(1) with stationary-site indoor, outdoor, and central-site gravimetric PM sub(2.5 ) and PM sub(10), and with hourly tapered-element oscillating microbalance PM sub(10). Personal PM was associated more strongly with FEV sub(1) than was stationary-site PM, and associations of FEV sub(1) with lag 0 indoor and outdoor home PM sub(2.5 ) and PM sub(10) were more significant and stronger than for central-site PM2.5 and PM10. Significantly stronger associations of FEV sub(1) with PM were found in boys than in girls.
ISSN:0091-6765
DOI:10.1289/ehp.6815