Study of the role of anaerobic metabolism in succinate production by Enterobacter aerogenes

Succinate is a core biochemical building block; optimizing succinate production from biomass by microbial fermentation is a focus of basic and applied biotechnology research. Lowering pH in anaerobic succinate fermentation culture is a cost-effective and environmentally friendly approach to reducing...

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Bibliographic Details
Published in:Applied microbiology and biotechnology 2014-09, Vol.98 (18), p.7803-7813
Main Authors: Tajima, Yoshinori, Kaida, Kenichi, Hayakawa, Atsushi, Fukui, Keita, Nishio, Yousuke, Hashiguchi, Kenichi, Fudou, Ryosuke, Matsui, Kazuhiko, Usuda, Yoshihiro, Sode, Koji
Format: Article
Language:English
Subjects:
Acids
anaerobic conditions
Anaerobiosis
Analysis
Bacteria
biochemical pathways
Biomass
Biomedical and Life Sciences
Biotechnological Products and Process Engineering
Biotechnology
Carbon
carboxylation
Chemicals
cost effectiveness
Dehydrogenases
E coli
Enterobacter
Enterobacter aerogenes
Enterobacter aerogenes - metabolism
Enterobacteriaceae
Ethanol
Fermentation
Fermentation - physiology
Glucose
Glycerol
knockout mutants
Life Sciences
metabolic engineering
Metabolism
Metabolites
Microbial Genetics and Genomics
Microbiology
NAD (coenzyme)
neutralization
Oxidation
Physiological aspects
Plasmids
R&D
Research & development
Studies
Succinates - metabolism
succinic acid
Succinic Acid - metabolism
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Summary:Succinate is a core biochemical building block; optimizing succinate production from biomass by microbial fermentation is a focus of basic and applied biotechnology research. Lowering pH in anaerobic succinate fermentation culture is a cost-effective and environmentally friendly approach to reducing the use of sub-raw materials such as alkali, which are needed for neutralization. To evaluate the potential of bacteria-based succinate fermentation under weak acidic (pH
ISSN:0175-7598
1432-0614
DOI:10.1007/s00253-014-5884-3