Has the cardiac stem cell controversy settled down

Although the human adult heart was considered a terminally differentiated organ and incapable of renewal after injury or with aging for almost a century, recent studies have shown that the heart is capable of new cardiomyocyte formation and possesses varying degrees of regenerative potential through...

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Bibliographic Details
Published in:Science China. Life sciences 2014-09, Vol.57 (9), p.949-950
Main Authors: Wu, MingFu, Meng, FanXia
Format: Article
Language:English
Subjects:
Adult
Biomedical and Life Sciences
Commentary
CSC
Humans
Life Sciences
Myocytes, Cardiac - cytology
Stem Cells - cytology
哺乳动物
干细胞
心肌细胞
心脏
终末分化
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Summary:Although the human adult heart was considered a terminally differentiated organ and incapable of renewal after injury or with aging for almost a century, recent studies have shown that the heart is capable of new cardiomyocyte formation and possesses varying degrees of regenerative potential throughout mammalian life. However, whether the cardiac stem cells （CSC） or the pre-existing cardiomyocytes con- tribute to the new cardiomyocyte formation remains con- troversial.
ISSN:1674-7305
1869-1889
DOI:10.1007/s11427-014-4690-6