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Golgi Apparatus: Finally Mechanics Comes to Play in the Secretory Pathway

New findings report a mechanical role for actin in Golgi organization and vesicular trafficking. An elegant study uses optical tweezers and live-cell imaging to demonstrate the effects of a mechanical constraint on the dynamics of secretory membrane trafficking, combining physical experimental appro...

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Bibliographic Details
Published in:Current biology 2014-08, Vol.24 (16), p.R741-R743
Main Authors: Egea, Gustavo, Serra-Peinado, Carla
Format: Article
Language:English
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Summary:New findings report a mechanical role for actin in Golgi organization and vesicular trafficking. An elegant study uses optical tweezers and live-cell imaging to demonstrate the effects of a mechanical constraint on the dynamics of secretory membrane trafficking, combining physical experimental approaches with in cellulo studies of endomembranes. New findings report a mechanical role for actin in Golgi organization and vesicular trafficking. An elegant study uses optical tweezers and live-cell imaging to demonstrate the effects of a mechanical constraint on the dynamics of secretory membrane trafficking, combining physical experimental approaches with in cellulo studies of endomembranes.
ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2014.07.002