Resurgence of intravenous Opana as a cause of secondary thrombotic thrombocytopenic purpura

[...]we want to report this case to increase awareness among the medical community (1) to advise patients being prescribed Opana about the risks involved if abused intravenously and (2) recognize Opana IV use as a possible cause of TTP when encountered in the inpatient setting. On physical examinati...

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Bibliographic Details
Published in:The American journal of emergency medicine 2014-08, Vol.32 (8), p.951.e3-951.e4
Main Authors: Rane, Meghan, MB, BS, PGY3, Aggarwal, Aakash, MB, BS, PGY3, Banas, Emerald, MD, PGY3, Sharma, Amit, MB, BS, MPH, PGY3
Format: Article
Language:English
Subjects:
Adult
Bioavailability
Emergency
Emergency medical care
Emergency Service, Hospital
Female
Humans
Illnesses
Infections
Mortality
Narcotics - adverse effects
Oxymorphone - adverse effects
Patients
Plasmapheresis
Purpura, Thrombotic Thrombocytopenic - chemically induced
Purpura, Thrombotic Thrombocytopenic - diagnosis
Purpura, Thrombotic Thrombocytopenic - therapy
Substance Abuse, Intravenous - complications
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Summary:[...]we want to report this case to increase awareness among the medical community (1) to advise patients being prescribed Opana about the risks involved if abused intravenously and (2) recognize Opana IV use as a possible cause of TTP when encountered in the inpatient setting. On physical examination, she was febrile at 38.5°C with a blood pressure of 142/108 mmHg, equal in both arms, tachycardic at 139 beats per minute, and tachypneic at 36 breaths per minute with 95% oxygen saturation on room air.
ISSN:0735-6757
1532-8171
DOI:10.1016/j.ajem.2014.01.058