Brachial-Ankle Pulse Wave Velocity for Predicting Functional Outcome in Acute Stroke

BACKGROUND AND PURPOSE—We investigated whether the brachial-ankle pulse wave velocity (baPWV) has prognostic value for predicting functional outcome after acute cerebral infarction and whether the prognostic value differs between stroke subtypes. METHODS—We included 1091 consecutive patients with fi...

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Bibliographic Details
Published in:Stroke (1970) 2014-08, Vol.45 (8), p.2305-2310
Main Authors: Kim, Jinkwon, Song, Tae-Jin, Kim, Eun Hye, Lee, Ki Jeong, Lee, Hye Sun, Nam, Chung Mo, Song, Dongbeom, Nam, Hyo Suk, Kim, Young Dae, Heo, Ji Hoe
Format: Article
Language:English
Subjects:
Aged
Ankle Brachial Index
Biological and medical sciences
Blood Flow Velocity - physiology
Brachial Artery - physiopathology
Brain Ischemia - drug therapy
Brain Ischemia - physiopathology
Female
Fibrinolytic Agents - therapeutic use
Headache. Facial pains. Syncopes. Epilepsia. Intracranial hypertension. Brain oedema. Cerebral palsy
Humans
Male
Medical sciences
Middle Aged
Nervous system (semeiology, syndromes)
Neurology
Predictive Value of Tests
Prognosis
Pulse Wave Analysis
Retrospective Studies
Stroke - drug therapy
Stroke - physiopathology
Tissue Plasminogen Activator - therapeutic use
Treatment Outcome
Vascular diseases and vascular malformations of the nervous system
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Summary:BACKGROUND AND PURPOSE—We investigated whether the brachial-ankle pulse wave velocity (baPWV) has prognostic value for predicting functional outcome after acute cerebral infarction and whether the prognostic value differs between stroke subtypes. METHODS—We included 1091 consecutive patients with first-ever acute cerebral infarction who underwent baPWV measurements. Stroke subtypes were classified using the Trial of Org 10172 in Acute Stroke Treatment classification. Poor functional outcomes were defined as modified Rankin Scale score >2 at 3 months after stroke onset. RESULTS—We noted that 181 (16.59%) patients had a poor functional outcome. In multivariate logistic regression, patients in the highest tertile of baPWV (>22.25 m/s) were found to be at increased risk for poor functional outcome (adjusted odds ratio, 1.88; 95% confidence interval, 1.06–3.40) compared with those in the lowest tertile (
ISSN:0039-2499
1524-4628
DOI:10.1161/STROKEAHA.114.005576