Guidelines for treating iron overload in myelodysplastic syndromes: a Taiwan consensus statement

Iron overload is common in myelodysplastic syndrome (MDS) patients, and an accumulation of evidence shows that iron chelation may have benefits in these patients. However, discussion and consensus about iron chelation therapy (ICT) for MDS patients is lacking in Taiwan and other Southeast Asian coun...

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Bibliographic Details
Published in:International journal of hematology 2014-07, Vol.100 (1), p.7-15
Main Authors: Ko, Bor-Sheng, Chang, Cheng-Shyong, Chang, Ming-Chih, Chen, Tsai Yun, Chiou, Tzeon-Jye, Chiu, Chang-Fang, Huang, Wen-Li, Kao, Woei-Yau, Lan, Yii-Jenq, Lin, Shen-Fung, Tan, Tran-Der, Tang, Jih-Luh, Tzeng, Cheng-Hwai, Wang, Po-Nan, Yet, Su-Pen, Tien, Hwei-Fang
Format: Article
Language:English
Subjects:
Biological and medical sciences
Chelation Therapy - methods
Guide Line
Hematologic and hematopoietic diseases
Hematology
Hematopoiesis - drug effects
Humans
Iron Chelating Agents - therapeutic use
Iron Overload - complications
Iron Overload - drug therapy
Iron Overload - etiology
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Medical sciences
Medicine
Medicine & Public Health
Metabolic diseases
Metals (hemochromatosis...)
Myelodysplastic syndromes
Myelodysplastic Syndromes - complications
Myelodysplastic Syndromes - epidemiology
Oncology
Other metabolic disorders
Practice Guidelines as Topic
Survival Analysis
Taiwan - epidemiology
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Description
Summary:Iron overload is common in myelodysplastic syndrome (MDS) patients, and an accumulation of evidence shows that iron chelation may have benefits in these patients. However, discussion and consensus about iron chelation therapy (ICT) for MDS patients is lacking in Taiwan and other Southeast Asian countries. An Expert Panel in Taiwan was organized in 2011 to develop iron overload guidelines and provide a uniform reference for physicians treating MDS patients with iron overload, with specific regard to when to initiate ICT, in which patients, and the clinical and scientific rationale behind its use.
ISSN:0925-5710
1865-3774
DOI:10.1007/s12185-014-1607-x