A Resectable Pancreatic Metastasis from Pulmonary Adenocarcinoma

A 67-year-old man, diagnosed as primary pulmonary adenocarcinoma by intraoperative fine-needle aspiration biopsy cytology, underwent right lower lobectomy with radical lymphadenectomy. The pathological stage was Stage IIA (pT1bN1M0, N-reason: 12Lpositive). After surgery, nodular shadows without intr...

Full description

Saved in:
Bibliographic Details
Published in:Annals of Thoracic and Cardiovascular Surgery 2014, Vol.20(3), pp.243-245
Main Authors: Igai, Hitoshi, Kamiyoshihara, Mitsuhiro, Nagashima, Toshiteru, Ohtaki, Yoichi, Shimizu, Kimihiro
Format: Article
Language:English
Subjects:
Adenocarcinoma - chemistry
Adenocarcinoma - secondary
Adenocarcinoma - surgery
Adenocarcinoma of Lung
Aged
Biomarkers, Tumor - analysis
Biopsy
Humans
Immunohistochemistry
Lung Neoplasms - chemistry
Lung Neoplasms - pathology
Lung Neoplasms - surgery
Lymph Node Excision
Male
Neoplasm Staging
Nuclear Proteins - analysis
pancreatic metastasis
Pancreatic Neoplasms - chemistry
Pancreatic Neoplasms - secondary
Pancreatic Neoplasms - surgery
Pancreaticoduodenectomy
Pneumonectomy
pulmonary adenocarcinoma
Thyroid Nuclear Factor 1
Tomography, X-Ray Computed
Transcription Factors - analysis
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:A 67-year-old man, diagnosed as primary pulmonary adenocarcinoma by intraoperative fine-needle aspiration biopsy cytology, underwent right lower lobectomy with radical lymphadenectomy. The pathological stage was Stage IIA (pT1bN1M0, N-reason: 12Lpositive). After surgery, nodular shadows without intrathoracic lymph node or distant metastasis were demonstrated metachronously three times by follow-up CT. Wedge resection was performed for each of the tumors, and the pathological diagnosis in each case was primary pulmonary adenocarcinoma, Stage IA (T1b), IA (T1a) and IA (T1a), respectively.Five years after the initial pulmonary resection, a follow-up abdominal CT revealed a20-mm nodular shadow. We suspected that this pancreatic tumor might be a primary rather than metastatic one, therefore, pancreatoduodenectomy was performed. Pathological examination revealed adenocarcinoma that was positive for thyroid transcription factor (TTF)-1, allowing a final diagnosis of metastatic pulmonary adenocarcinoma.This case is very rare, because most cases of pancreatic metastasis from lung cancer have already widespread disease at the time of diagnosis.This case illustrates that pancreatic metastasis from pulmonary adenocarcinoma should be borne in mind, even if the pancreatic tumor is a solitary lesion without additional organ metastasis.
ISSN:1341-1098
2186-1005
DOI:10.5761/atcs.cr.12.02049