Small cell neuroendocrine carcinoma of the uterine cervix: Report of six cases and a review of the literature

Neuroendocrine carcinoma is a rare and aggressive malignant tumour, mainly developing at the expense of the respiratory and of the digestive tract. Gynecological neuroendocrine tumours are rare and small cell neuroendocrine tumours of the uterine cervix represent 2% of cervical cancer. Given their r...

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Bibliographic Details
Published in:Cancer radiothérapie 2014-06, Vol.18 (3), p.201-207
Main Authors: Bellefqih, S, Khalil, J, Mezouri, I, Kebdani, T, Benjaafar, N
Format: Article
Language:fre
Subjects:
Adult
Antineoplastic Agents - therapeutic use
Carcinoma, Neuroendocrine - pathology
Carcinoma, Neuroendocrine - therapy
Carcinoma, Small Cell - pathology
Carcinoma, Small Cell - therapy
Chemotherapy, Adjuvant
Cisplatin - therapeutic use
Etoposide - therapeutic use
Female
Humans
Hysterectomy
Lymph Node Excision
Middle Aged
Neoplasm Metastasis
Radiotherapy, Adjuvant
Retrospective Studies
Uterine Cervical Neoplasms - pathology
Uterine Cervical Neoplasms - therapy
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Summary:Neuroendocrine carcinoma is a rare and aggressive malignant tumour, mainly developing at the expense of the respiratory and of the digestive tract. Gynecological neuroendocrine tumours are rare and small cell neuroendocrine tumours of the uterine cervix represent 2% of cervical cancer. Given their rarity and the lack of randomized trials, the diagnostic and therapeutic management of these tumors is difficult and essentially based on that of pulmonary neuroendocrine tumours. Like the latter, and despite multimodality regimens, the prognosis of these tumours remains poor. Through this series, we report our experience in the management of these particular tumours while comparing our data with those of the literature.
ISSN:1769-6658
DOI:10.1016/j.canrad.2014.01.003