Graphene for multi-functional synthetic biology: The last ‘zeitgeist’ in nanomedicine

The high versatility of graphene has attracted significant attention in many areas of scientific research from electronics to physics and mechanics. One of the most intriguing utilisation of graphene remains however in nanomedicine and synthetic biology. In particular, the last decade has witnessed...

Full description

Saved in:
Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 2014-04, Vol.24 (7), p.1638-1649
Main Authors: Servant, A., Bianco, A., Prato, M., Kostarelos, K.
Format: Article
Language:English
Subjects:
Antineoplastic Agents - chemical synthesis
Antineoplastic Agents - chemistry
Carbon
Drug delivery
Drug Design
Graphite - chemistry
Nanomaterials
Nanomedicine
Nanotechnology
Synthetic Biology
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:The high versatility of graphene has attracted significant attention in many areas of scientific research from electronics to physics and mechanics. One of the most intriguing utilisation of graphene remains however in nanomedicine and synthetic biology. In particular, the last decade has witnessed an exponential growth in the generation of novel candidate therapeutics of multiple biological activities based on graphene constructs with small molecules, such as anti-cancer drugs. In this Digest, we summarise the different synthetic strategies and routes available to fabricate these promising graphene conjugates and the opportunities for the design of multi-functional tools for synthetic biology that they offer.
ISSN:0960-894X
1464-3405
DOI:10.1016/j.bmcl.2014.01.051