Potassium Bromide for Treatment of Malignant Migrating Partial Seizures in Infancy

Abstract Background The syndrome of malignant migrating partial seizures in infancy is a rare epileptic syndrome with a devastating course characterized by early onset of continuous pharmacoresistent multifocal seizures arising from multiple independent sites of both hemispheres with unknown etiolog...

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Bibliographic Details
Published in:Pediatric neurology 2013-11, Vol.49 (5), p.355-357
Main Authors: Uenver, Olcay, Incecik, Faruk, Duendar, Huelya, Komuer, Mustafa, Uenver, Afsin, Okuyaz, Cetin
Format: Article
Language:English
Subjects:
Anticonvulsants - therapeutic use
Bromides - therapeutic use
Electroencephalography
Epilepsies, Partial - drug therapy
Humans
Infant
Male
malignant migrating partial seizures in infancy
Neurology
Pediatrics
potassium bromide
Potassium Compounds - therapeutic use
refractory epilepsy
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Summary:Abstract Background The syndrome of malignant migrating partial seizures in infancy is a rare epileptic syndrome with a devastating course characterized by early onset of continuous pharmacoresistent multifocal seizures arising from multiple independent sites of both hemispheres with unknown etiology. Patient A 2-month-old boy with the characteristic clinical and electroencephalograph pattern of migrating partial seizures in infancy was treated with potassium bromide. His seizures were unresponsive to the conventional and new generation antiepileptic drugs. Results The seizure frequency was reduced markedly with potassium bromide. Conclusions Potassium bromide, an old antiepileptic drug, is useful in the treatment of malignant migrating partial seizures in infancy.
ISSN:0887-8994
1873-5150
DOI:10.1016/j.pediatrneurol.2013.05.016