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The Liverpool uveal melanoma liver metastases pathway: Outcome following liver resection
Aim To determine the outcome of patients that underwent liver resection for metastases from uveal melanoma. Methods Over a 9‐year period, patients referred with uveal melanoma metastases were included. Following treatment of primary uveal melanoma, high‐risk patients were offered to be enrolled into...
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Published in: | Journal of surgical oncology 2014-05, Vol.109 (6), p.542-547 |
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Main Authors: | , , , , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Aim
To determine the outcome of patients that underwent liver resection for metastases from uveal melanoma.
Methods
Over a 9‐year period, patients referred with uveal melanoma metastases were included. Following treatment of primary uveal melanoma, high‐risk patients were offered to be enrolled into a 6‐monthly non‐contrast liver magnetic resonance imaging (MRI) surveillance. Following detection of liver metastases, patients were staged with a contrast‐enhanced (Primovist®) liver MRI, computer tomography (CT) of the thorax and staging laparoscopy.
Results
155 patients were referred with uveal melanoma liver metastases, of which 17 (11.0%) patients had liver resection and one patient was treated with percutaneous radio‐frequency ablation. The majority of patients undergoing liver resection were treated with multiple metastectomies (n = 8) and three patients had major liver resections. The overall median survival for patients treated with surgery/ablation was 27 (14–90) months, and this was significantly better compared to patients treated palliatively [median = 8(1–30) months, P |
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ISSN: | 0022-4790 1096-9098 |
DOI: | 10.1002/jso.23535 |