Radiological manifestations of abdominopelvic nerve tumours seen in neurofibromatosis type 1

Neurofibromatosis type 1 (NF1) is the most common of the phakomatoses, which is inherited in an autosomal dominant pattern. Neurofibromas arise from Schwann cells and fibroblasts and plexiform neurofibromas are pathognomonic for NF1, which may arise in any peripheral nerve. The clinical expression o...

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Bibliographic Details
Published in:Clinical radiology 2014-04, Vol.69 (4), p.431-435
Main Authors: Ozcan, H.N, Karcaaltincaba, M, Oguz, B, Haliloglu, M
Format: Article
Language:English
Subjects:
Adolescent
Adult
Child
Diagnosis, Differential
Female
Humans
Magnetic Resonance Imaging
Male
Nerve Sheath Neoplasms - diagnostic imaging
Nerve Sheath Neoplasms - pathology
Neurofibroma, Plexiform - diagnostic imaging
Neurofibroma, Plexiform - pathology
Neurofibromatosis 1 - diagnostic imaging
Neurofibromatosis 1 - pathology
Pelvis - innervation
Peripheral Nerves - pathology
Prognosis
Radiography, Abdominal
Radiology
Tomography, X-Ray Computed
Ultrasonography
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Summary:Neurofibromatosis type 1 (NF1) is the most common of the phakomatoses, which is inherited in an autosomal dominant pattern. Neurofibromas arise from Schwann cells and fibroblasts and plexiform neurofibromas are pathognomonic for NF1, which may arise in any peripheral nerve. The clinical expression of NF1 is extremely variable and gastrointestinal manifestations of NF1 are relatively uncommon. The purpose of this article is to illustrate the abdominal ultrasound, computed tomography, and magnetic resonance imaging findings of abdominopelvic nerve tumours seen in NF1 in both paediatric and adult patients.
ISSN:0009-9260
1365-229X
DOI:10.1016/j.crad.2013.11.007