Curative effect of heat-sensitive moxibustion on chronic persistent asthma： a multicenter randomized controlled trial

OBJECTIVE： To compare the curative effects of heat-sensitive moxibustion with conventional drugs on chronic persistent asthma and seek a valuable therapy to replaceWestern Medicine. METHODS： The participants in this multi-center, randomized, and controlled study were randomly divided into two groups...

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Published in:Journal of traditional Chinese medicine 2013-10, Vol.33 (5), p.584-591
Main Authors: Chen, Rixin, Chen, Mingren, Xiong, Jun, Chi, Zhenhai, Zhang, Bo, Tian, Ning, Xu, Zhenhua, Zhang, Tangfa, Li, Wanyao, Zhang, Wei, Rong, Xiaofeng, Wang, Zhen, Sun, Gang, Ge, Baohe, Yu, Guoxiong, Song, Nanchang
Format: Article
Language:English
Subjects:
Adolescent
Adult
Aged
Asthma - therapy
Chronic Disease - therapy
Female
Humans
Male
Middle Aged
Moxibustion - methods
Treatment Outcome
Young Adult
哮喘
多中心
慢性
持续性
热敏感
疗效
随机对照试验
频率测量
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Summary:OBJECTIVE： To compare the curative effects of heat-sensitive moxibustion with conventional drugs on chronic persistent asthma and seek a valuable therapy to replaceWestern Medicine. METHODS： The participants in this multi-center, randomized, and controlled study were randomly divided into two groups： group A（n=144）, treated with heat-sensitive moxibustion（50 sessions） and group B（n=144）, treated with Seretide（salmeterol 50 μg/fluticasone 250 μg, twice a day）. The scores of asthma control test（ACT）, forced expiratory volume in 1 second（FEV1）, peak expiratory flow（PEF）, and attack frequency were measured after 15, 30, 60, and 90 days of treatment. Patients followed up 3 and 6 months after treatment. RESULTS： There was a significant difference（P= 0.0002） in the ACT score and lung function between the two groups after 3 months of treatment and（P=0.000 03） during the follow-up visits. In addition, heat-sensitive moxibustion reduced attack frequency in the period from inclusion to the 6-month follow-up visit. CONCLUSION： This study shows that heat-sensitive moxibustion may have a comparable curative effect toSeretide（salmeterol/fluticasone） on asthma.
ISSN:0255-2922
DOI:10.1016/S0254-6272(14)60025-X