A clinical and biological evaluation of a novel, noninvasive radiofrequency device for the long-term reduction of adipose tissue

Background and Objective A novel, noninvasive technology, utilizing suction‐coupled radiofrequency (RF) heating and ultra‐short pulse duration, high‐voltage electrical pulses was studied for its efficacy and safety on adipose tissue reduction. Methods Twenty‐one subjects underwent treatment of their...

Full description

Saved in:
Bibliographic Details
Published in:Lasers in surgery and medicine 2014-02, Vol.46 (2), p.94-103
Main Authors: Boisnic, Sylvie, Divaris, Marc, Nelson, Andrew A., Gharavi, Nima M., Lask, Gary P.
Format: Article
Language:English
Subjects:
Abdomen
Ablation Techniques - instrumentation
Ablation Techniques - methods
adipose tissue
Adult
apoptosis
circumference reduction
Follow-Up Studies
Humans
irreversible electroporation
Lipectomy - instrumentation
Lipectomy - methods
Middle Aged
neocollagenosis
noninvasive fat destruction
Obesity, Abdominal - surgery
Radio Waves - therapeutic use
radiofrequency
Subcutaneous Fat, Abdominal - surgery
Suction - instrumentation
Treatment Outcome
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background and Objective A novel, noninvasive technology, utilizing suction‐coupled radiofrequency (RF) heating and ultra‐short pulse duration, high‐voltage electrical pulses was studied for its efficacy and safety on adipose tissue reduction. Methods Twenty‐one subjects underwent treatment of their abdominal fat once weekly for 6 weeks. Clinical outcomes including abdominal circumference, adipose tissue thickness (measured by ultrasound), adipose tissue weight, body weight, and clinical photographs were obtained at visits 1 and 3 months after last treatment. Adverse events were recorded. Three subjects, who were undergoing a future elective abdominoplasty, were treated with the same protocol, but on only one side of the abdomen before abdominoplasty. Biopsies from the RF‐treated and untreated sides were harvested during abdominoplasty and cultured; measurements of adipocyte size and shape, rate of apoptosis, collagen production, and dermal thickness were determined. Results Significant clinical improvements (P 
ISSN:0196-8092
1096-9101
DOI:10.1002/lsm.22223