Efficacy of modified constraint induced movement therapy in improving upper limb function in children with hemiplegic cerebral palsy: A randomized controlled trial

Abstract Purpose: The objective of this randomized single blind (outcome assessor) controlled trial was to evaluate the efficacy of 4 weeks of modified constraint induced movement therapy (mCIMT) in improving upper limb function in 3–8 years old children with hemiplegic cerebral palsy. Methods: Thir...

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Published in:Brain & development (Tokyo. 1979) 2013-10, Vol.35 (9), p.870-876
Main Authors: Choudhary, Anita, Gulati, Sheffali, Kabra, Madhulika, Singh, Upinder Pal, Sankhyan, Naveen, Pandey, Ravindra Mohan, Kalra, Veena
Format: Article
Language:English
Subjects:
Cerebral Palsy - physiopathology
Cerebral Palsy - therapy
Child
Child, Preschool
Exercise Therapy - methods
Female
Forced use therapy
Hand function
Hemiplegia - physiopathology
Hemiplegia - therapy
Hemiplegic cerebral palsy
Humans
Male
Movement - physiology
Neurology
Nine hole peg board
QUEST
Single-Blind Method
Treatment Outcome
Upper Extremity - physiopathology
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Summary:Abstract Purpose: The objective of this randomized single blind (outcome assessor) controlled trial was to evaluate the efficacy of 4 weeks of modified constraint induced movement therapy (mCIMT) in improving upper limb function in 3–8 years old children with hemiplegic cerebral palsy. Methods: Thirty-one children were randomly assigned to receive the mCIMT ( N = 16) with conventional therapy or conventional therapy alone ( N = 15). Children were evaluated three times (at enrollment, follow up at 4 weeks and 12 weeks). The primary outcome measure was difference in “change in mean total QUEST scores” at 4 weeks of intervention between the intervention and the control arm. Results: After 4 weeks of intervention, mCIMT group showed significant change in the affected upper limb in QUEST scores (10.7 ± 5.2 vs 1.4 ± 1.7, p < 0.001) and time (s) to complete nine-hole-pegboard test compared with control group [60(0–130) vs 5(−12 to 30), p < 0.001]. The improvement observed in upper limb function after 4 weeks of intervention persisted 8 weeks after discontinuation of intervention in mCIMT group. Conclusion: The modified constraint induced movement therapy appears to be effective in improving upper limb function in 3–8 years old hemiplegic cerebral palsy children.
ISSN:0387-7604
1872-7131
DOI:10.1016/j.braindev.2012.11.001