A coming of age: advanced imaging technologies for characterising the developing mouse

Highlights • International efforts are coming together to undertake mouse embryo phenotyping. • State-of-the-art 3D imaging has the potential to expedite this ambitious task. • We review rapid advances made in the imaging field over the past decade. • We examine the relative merits of current and em...

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Bibliographic Details
Published in:Trends in genetics 2013-12, Vol.29 (12), p.700-711
Main Authors: Norris, Francesca C, Wong, Michael D, Greene, Nicholas D.E, Scambler, Peter J, Weaver, Tom, Weninger, Wolfgang J, Mohun, Timothy J, Henkelman, R. Mark, Lythgoe, Mark F
Format: Article
Language:English
Subjects:
Animals
Diagnostic Imaging
Embryonic Development
high-resolution episcopic microscopy
magnetic resonance imaging
Medical Education
Mice
micro X-ray computed tomography
mouse embryo
optical projection tomography
phenotyping
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Summary:Highlights • International efforts are coming together to undertake mouse embryo phenotyping. • State-of-the-art 3D imaging has the potential to expedite this ambitious task. • We review rapid advances made in the imaging field over the past decade. • We examine the relative merits of current and emerging imaging techniques. • We discuss the potential shortcomings and the future of embryo imaging.
ISSN:0168-9525
DOI:10.1016/j.tig.2013.08.004