Acute toxoplasmosis-etiological factor for development of Hodgkin's lymphoma?

Abstract The case of an HIV-positive man treated for acute toxoplasmosis with no traces of malignancy is reported. A second lymph node extirpation was performed after 5 months, which identified the presence of Hodgkin and Reed-Sternberg (HRS) cells. This case suggests that toxoplasmosis may cause ch...

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Bibliographic Details
Published in:Scandinavian journal of infectious diseases 2013-12, Vol.45 (12), p.953-956
Main Authors: Snopkova, Svatava, Pohanka, Miroslav, Polak, Pavel, Havlickova, Katerina, Jarkovsky, Ji i, Moulis, Mojmir, Stroblova, Hana, Husa, Petr
Format: Article
Language:English
Subjects:
Adult
HIV Infections - complications
HIV Infections - parasitology
HIV Infections - pathology
Hodgkin Disease - parasitology
Hodgkin Disease - pathology
Hodgkin Disease - virology
Humans
Male
Reed-Sternberg Cells - cytology
Toxoplasmosis - complications
Toxoplasmosis - pathology
Toxoplasmosis - virology
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Summary:Abstract The case of an HIV-positive man treated for acute toxoplasmosis with no traces of malignancy is reported. A second lymph node extirpation was performed after 5 months, which identified the presence of Hodgkin and Reed-Sternberg (HRS) cells. This case suggests that toxoplasmosis may cause changes in the regulation of surrounding cells and induce neoplastic proliferation.
ISSN:0036-5548
1651-1980
DOI:10.3109/00365548.2013.807937