Clinical guidelines for sperm cryopreservation in cancer patients

No clear clinical guidelines exist on how to counsel male cancer patients about fertility preservation. Detailed counseling is recommended before treatment when issues of collection and storage need to be highlighted. Concern about the quality of sperm collected before and/or after treatment in term...

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Bibliographic Details
Published in:Fertility and sterility 2013-11, Vol.100 (5), p.1203-1209
Main Authors: Nangia, Ajay K., M.B.B.S, Krieg, Sacha A., M.D., Ph.D, Kim, S. Samuel, M.D
Format: Article
Language:English
Subjects:
Antineoplastic Agents - adverse effects
assisted reproductive technologies
Cancer treatment
chemotherapy
contraception
counseling
cryopreservation
Cryopreservation - standards
ethics
fertility preservation
Fertility Preservation - standards
guidelines
Humans
Infertility, Male - chemically induced
Infertility, Male - etiology
Infertility, Male - pathology
Infertility, Male - physiopathology
Infertility, Male - therapy
Internal Medicine
Male
Neoplasms - therapy
Obstetrics and Gynecology
patients
Practice Guidelines as Topic
radiation
Radiotherapy - adverse effects
risk
Risk Assessment
Risk Factors
Sperm Banks - standards
sperm cryopreservation
Sperm Retrieval - standards
Spermatogenesis - drug effects
Spermatogenesis - radiation effects
spermatozoa
Spermatozoa - drug effects
Spermatozoa - pathology
Spermatozoa - radiation effects
survival rate
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Summary:No clear clinical guidelines exist on how to counsel male cancer patients about fertility preservation. Detailed counseling is recommended before treatment when issues of collection and storage need to be highlighted. Concern about the quality of sperm collected before and/or after treatment in terms of assisted reproduction is needed, and the potential outcomes should be discussed early as part of cancer survivorship. The discussion should be sensitive and tailored to the ethical situation based on the age of the patient, the severity of the illness, the need to initiate treatment, and genetic risk. Cryopreservation should be attempted/achieved before cancer treatment is initiated. Cryopreservation should not be performed during treatment or for some time after treatment because of the chromosomal and structural damage to sperm from cancer treatment. Contraception should be instigated during this period.
ISSN:0015-0282
1556-5653
DOI:10.1016/j.fertnstert.2013.08.054