Ketamine for Treatment-Resistant Depression: Ready or Not for Clinical Use?

Treatment-resistant depression is a significant clinical problem with great morbidity and mortality. The report by Murrough et al. of their two-site randomized controlled clinical trial of ketamine in patients with treatment-resistant depression is an exciting and important step in evaluating a new...

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Bibliographic Details
Published in:The American journal of psychiatry 2013-10, Vol.170 (10), p.1079-1081
Main Author: Rush, A. John
Format: Article
Language:English
Subjects:
Antidepressive Agents - therapeutic use
Depressive Disorder, Major - drug therapy
Depressive Disorder, Treatment-Resistant - drug therapy
Excitatory Amino Acid Antagonists - therapeutic use
Female
Humans
Ketamine - therapeutic use
Male
Mental depression
Pharmacology
Psychiatry
Citations: Items that cite this one
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Summary:Treatment-resistant depression is a significant clinical problem with great morbidity and mortality. The report by Murrough et al. of their two-site randomized controlled clinical trial of ketamine in patients with treatment-resistant depression is an exciting and important step in evaluating a new and promising approach for these patients.
ISSN:0002-953X
1535-7228
DOI:10.1176/appi.ajp.2013.13081034