Comparison of the histologic changes in conchae induced by radiofrequency thermal ablation and submucosal diathermy

Objective of study was to determine the histological change induced in the conchae by submucosal diathermy and radiofrequency thermal ablation, two techniques used in the treatment of lower conchal hypertrophy, and to compare the two methods to each other. The study was performed on 15 rabbits. Radi...

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Bibliographic Details
Published in:European archives of oto-rhino-laryngology 2013-11, Vol.270 (11), p.2901-2907
Main Authors: Kaplama, Mehmet Erkan, Kaygusuz, Irfan, Akpolat, Nusret, Karlidag, Turgut, Keles, Erol, Alpay, Hayrettin Cengiz, Yalcin, Sinasi, Orhan, Israfil
Format: Article
Language:English
Subjects:
Animals
Catheter Ablation
Cilia - pathology
Diathermy
Electrocoagulation
Fibrosis
Goblet Cells - pathology
Head and Neck Surgery
Medicine
Medicine & Public Health
Nasal Mucosa - immunology
Nasal Mucosa - pathology
Neurosurgery
Otorhinolaryngology
Rabbits
Rhinology
Turbinates - immunology
Turbinates - pathology
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Summary:Objective of study was to determine the histological change induced in the conchae by submucosal diathermy and radiofrequency thermal ablation, two techniques used in the treatment of lower conchal hypertrophy, and to compare the two methods to each other. The study was performed on 15 rabbits. Radiofrequency was applied to the study animals in Group I ( n  = 5) and submucosal diathermy to Group II ( n  = 5), while Group III ( n  = 5) was the untreated control. The animals were decapitated 21 days after treatment and their conchae nasales ventrales excised on both sides. Histology slides were prepared and evaluated by light microscopy for ciliary loss, increase in submucosal vascularity, loss of goblet cells, inflammatory cellular infiltration, fibrosis and epithelial damage. The differences between Groups I and III were not significant regarding ciliary loss, increase in submucosal vascularity, loss of goblet cells and epithelial damage ( p  > 0.05), while the inflammatory cellular infiltration and fibrosis were significantly different between these groups ( p  
ISSN:0937-4477
1434-4726
DOI:10.1007/s00405-013-2413-4