Synchronous bilateral inverted papilloma of the temporal bone: Case report and review of the literature

Background Temporal bone inverted papilloma (IP) is an extremely rare tumor. Its etiology is unknown and represents a source of debate. Only 2 previous cases of bilateral temporal bone IP have been reported. A case report and review of the literature via PubMed database search are presented. Mathods...

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Bibliographic Details
Published in:Head & neck 2013-08, Vol.35 (8), p.E240-E245
Main Authors: Ramey, Stephen J., Russo, J. Kyle, Condrey, Jack M., Coulter, Benjamin, Sharma, Anand K., Andersen, Peter
Format: Article
Language:English
Subjects:
bilateral
Carcinoma, Squamous Cell - pathology
Carcinoma, Squamous Cell - therapy
Cell Transformation, Neoplastic - pathology
Humans
inverted papilloma
Male
Middle Aged
Neoplasms, Multiple Primary - pathology
Neoplasms, Multiple Primary - therapy
Papilloma, Inverted - pathology
Papilloma, Inverted - therapy
Schneiderian
Skull Neoplasms - pathology
Skull Neoplasms - therapy
squamous cell carcinoma
temporal
Temporal Bone
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Summary:Background Temporal bone inverted papilloma (IP) is an extremely rare tumor. Its etiology is unknown and represents a source of debate. Only 2 previous cases of bilateral temporal bone IP have been reported. A case report and review of the literature via PubMed database search are presented. Mathods and Results A 52‐year‐old African‐American man who initially underwent medial maxillectomy for right‐sided nasal IP returned with bilateral temporal bone IP 7 months later without evidence of extension through the Eustachian tubes. Despite multiple resections and adjuvant radiation, the tumor transformed into squamous cell carcinoma and progressed to involve the intracranial dura, temporal lobe, and cervical dura. Conclusions Multiple origins may exist for temporal IP: direct extension, iatrogenic seeding, or development from ectopic Schneiderian epithelium. Temporal bone IP appears to represent a much more aggressive tumor than its nasal counterpart, necessitating aggressive early surgical intervention to decrease recurrence and transformation risk. © 2012 Wiley Periodicals, Inc. Head Neck, 2013
ISSN:1043-3074
1097-0347
DOI:10.1002/hed.23073