Apolipoprotein E, brain injury and neurodevelopmental outcome of children

Apolipoprotein E plays an important role in neurodegenerative processes in adulthood, whereas its neurodevelopmental role is uncertain. We aimed to study the effect of apolipoprotein E on neurodevelopment in a cohort liable to neurodevelopmental changes. The cohort consisted of very preterm (

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Bibliographic Details
Published in:Genes, brain and behavior brain and behavior, 2013-04, Vol.12 (3), p.348-352
Main Authors: Korja, M., Ylijoki, M., Lapinleimu, H., Pohjola, P., Matomäki, J., Kuśmierek, H., Mahlman, M., Rikalainen, H., Parkkola, R., Kaukola, T., Lehtonen, L., Hallman, M., Haataja, L.
Format: Article
Language:English
Subjects:
Age
APOE
Apolipoprotein E
Apolipoproteins
Apolipoproteins E - genetics
Babies
Biological and medical sciences
Birth weight
Brain Injuries - diagnostic imaging
Brain Injuries - genetics
brain injury
BSID‐II, FSIQ
Child clinical studies
Child Development
Diseases of mother, fetus and pregnancy
Female
Genotype
Gynecology. Andrology. Obstetrics
Humans
Infant, Extremely Premature
Infant, Newborn
Infant, Very Low Birth Weight
Longitudinal Studies
Magnetic Resonance Imaging
Male
Medical sciences
neurodevelopment
Organic mental disorders. Neuropsychology
Pregnancy. Fetus. Placenta
preterm
Psychology. Psychoanalysis. Psychiatry
Psychomotor Disorders - diagnostic imaging
Psychomotor Disorders - genetics
Psychopathology. Psychiatry
Ultrasonic imaging
Ultrasonography
very low birth weight
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Description
Summary:Apolipoprotein E plays an important role in neurodegenerative processes in adulthood, whereas its neurodevelopmental role is uncertain. We aimed to study the effect of apolipoprotein E on neurodevelopment in a cohort liable to neurodevelopmental changes. The cohort consisted of very preterm (
ISSN:1601-1848
1601-183X
DOI:10.1111/gbb.12024